Dodgers vs. Padres prediction: Dodgers favored to win Monday's MLB matchup [5/18/2026]

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Written by Dave Garofolo

Get Los Angeles Dodgers vs San Diego Padres predictions for MLB Monday.

Los Angeles Dodgers-San Diego Padres Predictions and Game Preview.
Los Angeles Dodgers vs. San Diego Padres MLB prediction for Monday, May 18, 2026.

The San Diego Padres will take on the Los Angeles Dodgers in MLB action at Petco Park on Monday, commencing at 9:40 PM ET.

The Padres will send Michael King (3-2, 2.63 ERA) to the mound, while the Dodgers have opted for Yoshinobu Yamamoto (3-3, 3.60 ERA).

Based on updated simulations, Dimers' advanced MLB model predicts the Dodgers as the most likely winner of the Dodgers vs. Padres game.

This article offers further insights into Monday's matchup, including best bets and picks.

Dodgers vs. Padres prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Dodgers and Padres, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Dodgers a 57% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 56% chance of covering the run line, while the over/under total of seven runs has a 58% chance of going over.

 

Dodgers vs. Padres odds [5/18/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Padres
Run Line -1.5 (+114) +1.5 (-130)
Moneyline -149 +130
Total o7 (-125) u7 (+105)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Padres picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Padres +1.5 -130
Moneyline Padres +130
Total Over 7 -125

According to our MLB best bets, the top play to make on this game is Over 7 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Padres game-day updates and essential details

Monday's MLB action between the Padres and Dodgers at Petco Park is scheduled to start at 9:40 PM ET.

Conclusion

We predict the Dodgers, with a 57% win probability, will likely beat the Padres in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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