May 18, 2026
MLB picks today: Monday's MLB best bets include Giants vs. Diamondbacks play [5/18/2026]
Read Article Guardians vs. Tigers prediction: Detroit favored to win Monday's MLB matchup [5/18/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Cleveland Guardians vs Detroit Tigers predictions for MLB Monday.
The Detroit Tigers will face the Cleveland Guardians in MLB action at Comerica Park on Monday, commencing at 6:40 PM ET.
Framber Valdez (2-2, 4.32 ERA) will be on the bump for the Tigers, pitting him against Slade Cecconi (2-4, 5.60 ERA) for the Guardians.
Based on the latest simulations, Dimers' advanced MLB model predicts the Tigers as the most likely winner of the Guardians vs. Tigers game.
This article offers an expanded analysis of Monday's matchup, including best bets and picks.
Guardians vs. Tigers prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Monday's MLB game between the Guardians and Tigers, forming part of our MLB predictions coverage.
Our independent predictive model gives the Tigers a 61% chance of beating the Guardians.
According to our model, the Guardians (+1.5) have a 57% chance of covering the run line, while the 8-run over/under has a 54% chance of going over.
Guardians vs. Tigers odds [5/18/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Guardians | Tigers |
|---|---|---|
| Run Line | +1.5 (-170) | -1.5 (+145) |
| Moneyline | +129 | -148 |
| Total | o8 (-110) | u8 (-105) |
All odds are correct at the time of publication and are subject to change.
Guardians vs. Tigers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Tigers -1.5 | +145 |
| Moneyline | Tigers | -148 |
| Total | Over 8 | -110 |
According to our MLB best bets, the top play to make on this game is Tigers -1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Guardians vs. Tigers game-day updates and essential details
Monday's MLB game between the Tigers and Guardians at Comerica Park is scheduled to commence at 6:40 PM ET.
- Who: Cleveland Guardians vs. Detroit Tigers
- Date: Monday, May 18, 2026
- Time: 6:40 PM ET/3:40PM PT
- Venue: Comerica Park
Conclusion
We predict the Tigers, with a 61% win probability, will likely beat the Guardians in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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