May 22, 2026
Tigers vs. Orioles prediction: Baltimore favored to win Friday's MLB matchup [5/22/2026]
Read Article Dodgers vs. Brewers prediction: Why Dodgers are favored to win Friday's MLB matchup [5/22/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Los Angeles Dodgers vs Milwaukee Brewers predictions for MLB Friday.
MLB action continues on Friday at 7:40 PM ET as the Los Angeles Dodgers lock horns with the Milwaukee Brewers at American Family Field.
Logan Henderson (1-1, 3.50 ERA) will be on the bump for the Brewers, pitting him against Justin Wrobleski (6-1, 2.49 ERA) for the Dodgers.
Based on updated simulation results, Dimers' advanced MLB model gives the Dodgers a slight edge with a 51% win probability over the Brewers.
This article offers a closer look at Friday's Dodgers vs. Brewers matchup, including best bets and picks.
Dodgers vs. Brewers prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the result of Friday's MLB game between the Dodgers and Brewers, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Dodgers a 51% chance of defeating the Brewers.
According to our model, the Brewers (+1.5) have a 61% chance of covering the run line, while the over/under total of 8.5 runs has a 53% chance of going over.
Dodgers vs. Brewers odds [5/22/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Dodgers | Brewers |
|---|---|---|
| Run Line | -1.5 (+152) | +1.5 (-180) |
| Moneyline | -110 | -104 |
| Total | o8.5 (-105) | u8.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Dodgers vs. Brewers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Dodgers -1.5 | +152 |
| Moneyline | Dodgers | -110 |
| Total | Over 8.5 | -105 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Dodgers vs. Brewers game-day updates and essential details
Friday's MLB matchup between the Brewers and Dodgers at American Family Field is scheduled to begin at 7:40 PM ET.
- Who: Los Angeles Dodgers vs. Milwaukee Brewers
- Date: Friday, May 22, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: American Family Field
Conclusion
We predict the Dodgers, with a 51% win probability, will likely beat the Brewers in Friday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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