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Dodgers vs. Astros prediction: Dodgers favored to win Monday's MLB matchup [5/4/2026]
Get Los Angeles Dodgers vs Houston Astros predictions for MLB Monday.

The Houston Astros and Los Angeles Dodgers are scheduled to meet in MLB action at Daikin Park on Monday, starting at 8:10 PM ET.
The Astros will have Steven Okert (0-0, 4.20 ERA) as their starting pitcher, up against Yoshinobu Yamamoto (2-2, 2.87 ERA) for the Dodgers.
Based on updated simulation results, Dimers' proven MLB model projects the Dodgers as the most likely winner of the Dodgers vs. Astros game.
This article offers further insights into Monday's matchup, including best bets and picks.
Dodgers vs. Astros prediction: Who will win and cover?
Our famous predictive model gives the Dodgers a 60% chance of beating the Astros.
According to our model, the Astros (+1.5) have a 51% chance of covering the run line, while the over/under total of nine runs has a 54% chance of going over.
Dodgers vs. Astros odds [5/4/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Dodgers | Astros |
|---|---|---|
| Run Line | -1.5 (-122) | +1.5 (+105) |
| Moneyline | -199 | +170 |
| Total | o9 (-115) | u9 (-105) |
All odds are correct at the time of publication and are subject to change.
Dodgers vs. Astros picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | +105 |
| Moneyline | Astros | +170 |
| Total | Over 9 | -115 |
According to our best MLB bets, the top play to make on this game is Astros to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Dodgers vs. Astros game-day updates and essential details
Monday's MLB game between the Astros and Dodgers at Daikin Park is scheduled to commence at 8:10 PM ET.
- Who: Los Angeles Dodgers vs. Houston Astros
- Date: Monday, May 4, 2026
- Time: 8:10 PM ET/5:10PM PT
- Venue: Daikin Park
Conclusion
We predict the Dodgers, with a 60% win probability, will likely beat the Astros in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
