Clippers vs. Hornets prediction: Why Clippers are favored to win Saturday's NBA matchup [11/22/2025]

NBA action continues on Saturday at 1:00PM ET as the Los Angeles Clippers take on the Charlotte Hornets at Spectrum Center.

Based on the latest simulations and today’s injury updates, Dimers' advanced NBA model predicts the Clippers as the most likely winner of the Clippers vs. Hornets game.

This prediction follows the latest NBA Injury Report, which suggests the Hornets lineup will feature stars like LaMelo Ball, Miles Bridges and Kon Knueppel, while the Clippers will look to James Harden, Ivica Zubac and John Collins.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Clippers vs. Hornets prediction: Who will win and cover?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Saturday's clash between the Clippers and Hornets.

Our leading predictive model currently gives the Clippers a 55% chance of defeating the Hornets. Our predicted final score has the Clippers winning 114-113.

According to our model, the Hornets (-1.5) have a 53% chance of covering the spread, while the over/under total of 227.5 points has a 51% chance of staying under.

Clippers vs. Hornets odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Clippers	Hornets
Spread	+1.5 (-114)	-1.5 (-102)
Moneyline	-102	-108
Total	o227.5 (-110)	u227.5 (-105)

All odds are correct at the time of publication and are subject to change.

Clippers vs. Hornets picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Hornets -1.5	-102
Moneyline	Clippers	-102
Total	Under 227.5	-105

According to our best NBA bets for Saturday, the top play to make on this game is Clippers to win.

Clippers vs. Hornets player props

NBA prop bets are an enjoyable way to wager on the LA Clippers vs. Charlotte matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Spectrum Center.

James Harden is expected to lead the Clippers with 26 points, 6 rebounds and 9 assists, while LaMelo Ball is projected to have 22 points, 5 rebounds and 7 assists for the Hornets.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Clippers prediction

Our model's projected player stats for the Clippers are:

Player	PTS	REB	AST	3PM	DFS
James Harden	26	6	9	3	54
Ivica Zubac	17	11	3	0	39
John Collins	16	6	1	2	30
B. Bogdanovic	12	4	3	2	25
Kobe Sanders	11	3	2	2	22

Hornets prediction

Projected points, rebounds, assists and three-pointers made for the Hornets:

Player	PTS	REB	AST	3PM	DFS
LaMelo Ball	22	5	7	3	45
Miles Bridges	20	7	4	3	40
Kon Knueppel	18	6	3	3	35
Brandon Miller	16	3	3	3	29
Collin Sexton	14	2	4	1	26

Clippers vs. Hornets game-day updates and essential details

Saturday's action between the Hornets and Clippers at Spectrum Center is scheduled to start at 1:00PM ET.

• Who: Los Angeles Clippers vs. Charlotte Hornets
• Date: Saturday, November 22, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Spectrum Center

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Conclusion

We predict the Clippers, with a 55% win probability, will likely beat the Hornets on Saturday, with James Harden projected for a game-high 54 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Clippers vs. Hornets insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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