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LIU vs. Mississippi State prediction: Why Mississippi State is favored to win men's college basketball matchup [12/16/2025]

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Written by Dave Garofolo

Get LIU vs Mississippi State predictions for college basketball Tuesday.

LIU-Mississippi State Predictions and Game Preview.
LIU vs. Mississippi State men's college basketball prediction for Tuesday, December 16, 2025.

Mississippi State will square off with LIU in men's college basketball action at Humphrey Coliseum on Tuesday, beginning at 7:30 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Mississippi State as the most likely winner of the LIU vs. Mississippi State game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

LIU vs. Mississippi State prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball game between LIU and Mississippi State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Mississippi State a 92% chance of defeating LIU. Our predicted final score has Mississippi State winning 85-68.

According to our model, the bookies have got it right, and LIU and Mississippi State each have a 50% chance of covering the spread, while the over/under total of 152.5 points has a 52% chance of going over.

 

LIU vs. Mississippi State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type LIU Mississippi State
Spread +16.5 (-110) -16.5 (-105)
Moneyline +1100 -1600
Total o152.5 (-108) u152.5 (-110)

All odds are correct at the time of publication and are subject to change.

LIU vs. Mississippi State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Mississippi State -16.5 -105
Moneyline LIU +1100
Total Over 152.5 -108

According to our men's college basketball best bets, the top play to make on this game is Over 152.5 total points.

 

LIU vs. Mississippi State game-day updates and essential details

Tuesday's men's college basketball game between Mississippi State and LIU at Humphrey Coliseum is scheduled to commence at 7:30 PM ET.

  • Who: LIU vs. Mississippi State
  • Date: Tuesday, December 16, 2025
  • Time: 7:30 PM ET/4:30PM PT
  • Venue: Humphrey Coliseum

Conclusion

We predict Mississippi State, with a 92% win probability, will likely beat LIU on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate LIU vs. Mississippi State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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