Jackson State vs. Houston prediction: Houston favored to win men's college basketball matchup [12/10/2025]

Men's college basketball action continues on Wednesday at 8:00PM ET as Jackson State locks horns with Houston in men's college basketball action at Fertitta Center.

Based on updated simulation results, Dimers' advanced college basketball model projects Houston as the most likely winner of the Jackson State vs. Houston game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Jackson State vs. Houston prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's NCAA basketball matchup between Jackson State and Houston 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Houston a 100% chance of defeating Jackson State. Our predicted final score has Houston winning 85-52.

According to our model, Jackson State (+40.5) has a 59% chance of covering the spread, while the over/under total of 138.5 points has a 51% chance of going over.

Jackson State vs. Houston odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Jackson State vs. Houston picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: