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Indiana vs. Kentucky prediction: Kentucky favored to win men's college basketball matchup [12/13/2025]
Get Indiana vs Kentucky predictions for college basketball Saturday.

Kentucky will face Indiana in men's college basketball action at Rupp Arena on Saturday, starting at 7:30PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts Kentucky as the most likely winner of the Indiana vs. Kentucky game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Indiana vs. Kentucky prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Indiana and Kentucky 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Kentucky a 65% chance of beating Indiana. Our predicted final score has Kentucky winning 80-76.
According to our model, Kentucky (-3.5) has a 56% chance of covering the spread, while the 156.5-point over/under has a 52% chance of going over.
Indiana vs. Kentucky odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Indiana | Kentucky |
|---|---|---|
| Spread | +3.5 (-110) | -3.5 (-110) |
| Moneyline | +142 | -170 |
| Total | o156.5 (-108) | u156.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Indiana vs. Kentucky picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Kentucky -3.5 | -110 |
| Moneyline | Kentucky | -170 |
| Total | Over 156.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is Kentucky -3.5 at the spread.
Indiana vs. Kentucky game-day updates and essential details
Saturday's men's college basketball game between Kentucky and Indiana at Rupp Arena is scheduled to start at 7:30PM ET.
- Who: Indiana vs. Kentucky
- Date: Saturday, December 13, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: Rupp Arena
Conclusion
We predict Kentucky, with a 65% win probability, will likely beat Indiana on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Indiana vs. Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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