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Pacers vs. Pistons prediction: Detroit favored to win Monday's NBA matchup [11/17/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Indiana Pacers vs Detroit Pistons predictions for NBA Monday.
The Detroit Pistons will square off with the Indiana Pacers in NBA action at Little Caesars Arena on Monday, starting at 7:00PM ET.
Based on the latest simulations and today’s injury updates, Dimers' proven NBA model predicts the Pistons as the most likely winner of the Pacers vs. Pistons game.
This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature stars like Cade Cunningham, Jalen Duren and Ausar Thompson, while the Pacers will be led by Pascal Siakam, Bennedict Mathurin and Andrew Nembhard.
This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pacers vs. Pistons prediction: Who will win and cover?
As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Monday's clash between the Pacers and Pistons.
According to our model, the Pacers (+8.5) have a 53% chance of covering the spread, while the over/under total of 230.5 points has a 51% chance of staying under.
Pacers vs. Pistons odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Pacers | Pistons |
|---|---|---|
| Spread | +8.5 (-110) | -8.5 (-105) |
| Moneyline | +300 | -335 |
| Total | o230.5 (-110) | u230.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Pacers vs. Pistons picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +8.5 | -110 |
| Moneyline | Pacers | +300 |
| Total | Under 230.5 | -110 |
According to our best NBA bets for Monday, the top play to make on this game is Pacers +8.5 at the spread.
Pacers vs. Pistons player props
Betting on Pacers vs. Pistons NBA prop bets? We use the best information available to project how each team's leading players will perform at Little Caesars Arena.
Pascal Siakam is expected to lead the Pacers with 22 points, 6 rebounds and 4 assists, while Cade Cunningham is projected to have 30 points, 5 rebounds and 8 assists for the Pistons.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Pacers prediction
Our model's projected player stats for the Pacers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 22 | 6 | 4 | 2 | 41 |
| B. Mathurin | 17 | 5 | 1 | 1 | 29 |
| Andrew Nembhard | 15 | 3 | 5 | 2 | 32 |
| Jarace Walker | 10 | 4 | 3 | 2 | 24 |
| T.J. McConnell | 9 | 2 | 3 | 0 | 20 |
Pistons prediction
Projected points, rebounds, assists and three-pointers made for the Pistons:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Cade Cunningham | 30 | 5 | 8 | 2 | 56 |
| Jalen Duren | 17 | 12 | 3 | 0 | 42 |
| Ausar Thompson | 15 | 6 | 3 | 0 | 34 |
| Duncan Robinson | 13 | 2 | 2 | 3 | 22 |
| Isaiah Stewart | 9 | 7 | 2 | 1 | 26 |
Pacers vs. Pistons game-day updates and essential details
Monday's matchup between the Pistons and Pacers at Little Caesars Arena is scheduled to begin at 7:00PM ET.
- Who: Indiana Pacers vs. Detroit Pistons
- Date: Monday, November 17, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Little Caesars Arena
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Conclusion
We predict the Pistons, with a 74% win probability, will likely beat the Pacers on Monday, with Cade Cunningham projected for a game-high 56 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pacers vs. Pistons insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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