Illinois vs. Iowa CFB Predictions and Odds - Nov 20, 2021

College Football Week 12 action continues on Saturday at 2:00 PM EST as Illinois takes on Iowa at Kinnick Stadium.

Dimers' top betting picks for Illinois vs. Iowa, as well as our score prediction and best odds, are featured in this article.

Who will win Illinois vs. Iowa?

Based on trusted computer power and data, Dimers.com has simulated Saturday's Illinois-Iowa NCAA Football matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives Iowa an 85% chance of defeating Illinois.

MORE: Full betting guide for Illinois vs. Iowa

Illinois vs. Iowa Point Spread, Moneyline and Over/Under

Iowa is the -12.5 favorite against Illinois, with -108 at FanDuel Sportsbook the best odds available.

For the underdog Illinois (+12.5) to cover the spread, FanDuel Sportsbook also has the best odds on offer at -112.

PointsBet has the best moneyline odds for Iowa at -470, which means you can risk $470 to win $100, for a total payout of $570, if it gets the W.

Elsewhere, FanDuel Sportsbook has the best moneyline odds for Illinois at +390, where you can bet $100 to profit $390, earning a total payout of $490, if it wins.

The Over/Under for total points scored is set at 38.5 with DraftKings Sportsbook, which has the best odds for the Over at +100, while Caesars Sportsbook has the best odds for the Under at -110.

As always, make sure you check all the sportsbooks that are available in your state for the best College Football odds and lines.

According to DimersBOT, Illinois (+12.5) is a 52% chance of covering the spread, while the Over/Under total of 38.5 points is a 53% chance of going Under.

MORE: Predictions and best bets for every College Football game

Best Bets for Illinois vs. Iowa

• Spread: Illinois +12.5 at -112 with FanDuel Sportsbook (52% probability)
• Moneyline: Iowa Win at -470 with PointsBet (85% probability)
• Over/Under: Under 38.5 at -110 with Caesars Sportsbook (53% probability)

Illinois vs. Iowa Score Prediction

Dimers.com's predicted final score for Illinois vs. Iowa at Kinnick Stadium on Saturday has Iowa winning 25-13.

Dimers has full betting coverage of this week's Illinois-Iowa matchup, including pre-game predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this page for any changes before Illinois vs. Iowa on Saturday November 20, 2021.

Illinois vs. Iowa 2021 CFB Game Info

When does Iowa play Illinois in College Football?

• Date: Saturday November 20, 2021
• Time: 2:00 PM EST / 11:00 AM PST
• Venue: Kinnick Stadium

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We use the power of predictive analytics to find edges in the markets so we can write the most comprehensive CFB betting previews available. We do this by comparing our dynamic and accurate probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

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