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Houston Astros vs. Chicago Cubs Prediction, Odds, MLB Picks [4/25/2024]

Houston Astros vs. Chicago Cubs Prediction, Odds, MLB Picks [4/25/2024]

MLB action continues on Thursday at 2:20PM ET as the Houston Astros square off with the Chicago Cubs at Wrigley Field.

The Cubs will have Javier Assad (2-0, 2.11 ERA) as their starting pitcher, up against Justin Verlander (1-0, 3.00 ERA) for the Astros.

Dimers.com's comprehensive preview of Thursday's Astros vs. Cubs matchup includes our prediction, picks and the latest betting odds.

JOIN NOW: Dimers Pro unlocks +EV bets daily. We give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join Dimers Pro now for less than $1 a day!

Astros vs. Cubs Prediction: Who Will Win, Cover the Run Line

We have used innovative machine learning and statistics to simulate the result of Thursday's MLB matchup between the Astros and Cubs 10,000 times, in keeping with our coverage of MLB picks.

Our famous predictive analytics model gives the Astros a 52% chance of defeating the Cubs.

According to our model, the Cubs (+1.5) have a 61% chance of covering the run line, while the 7.5-run over/under has a 51% chance of going over.

Astros vs. Cubs Odds [4/25/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Astros Cubs
Run Line -1.5 (+124) +1.5 (-145)
Moneyline -140 +120
Total o7.5 (+100) u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

Astros vs. Cubs Picks

At Dimers, our predictions, coupled with the best odds, reveal the top betting picks to make on every game, including Astros vs. Cubs. Our MLB best bets are based on expert modeling and analysis, as you can see.

Dimers Pro gives sports bettors an edge. Through Dimers Pro, we give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join now to find any potential picks for this matchup.


Astros vs. Cubs Game Information

Thursday's MLB action between the Cubs and Astros at Wrigley Field is scheduled to start at 2:20PM ET.


Our full betting coverage of the Astros vs. Cubs includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.


We predict the Astros, with a 52% win probability, will likely beat the Cubs on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

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Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

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