Houston Astros vs. Chicago Cubs Prediction, Odds, MLB Picks [4/24/2024]

Houston Astros vs. Chicago Cubs Prediction, Odds, MLB Picks [4/24/2024]

The Chicago Cubs and Houston Astros will lock horns in MLB action at Wrigley Field on Wednesday, starting at 7:40PM ET.

Jameson Taillon (1-0, 1.80 ERA) will get the ball for the Cubs, up against Spencer Arrighetti (0-2, 11.57 ERA) for the Astros.

Dimers.com's in-depth preview of Wednesday's Astros vs. Cubs matchup includes our prediction, picks and the latest betting odds.

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Astros vs. Cubs Prediction: Who Will Win, Cover the Run Line

We have used powerful machine learning and data analysis to simulate the outcome of Wednesday's MLB game between the Astros and Cubs 10,000 times, in line with our coverage of MLB picks.

Our proven predictive analytics model currently can't split the two teams, giving both the Astros and Cubs a 50% chance of winning the game.

According to our model, the Cubs (+1.5) have a 64% chance of covering the run line, while the 7.5-run over/under has a 54% chance of going over.

Astros vs. Cubs Odds [4/24/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Astros Cubs
Run Line -1.5 (+165) +1.5 (-185)
Moneyline -105 -105
Total o7.5 (-110) u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

Astros vs. Cubs Picks

At Dimers, our predictions, paired with the best odds, reveal the top betting picks to make on every game, including Astros vs. Cubs. Our best MLB bets are based on expert modeling and analysis, as you can see.

Improve your odds with Dimers Pro. Join Dimers Pro now to get exclusive access to hundreds of data-driven bets daily across thousands of games, including the ability to see any potential picks for this matchup.


Astros vs. Cubs Game Information

Wednesday's MLB game between the Cubs and Astros at Wrigley Field is scheduled to commence at 7:40PM ET.


Our full betting coverage of the Astros vs. Cubs includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Best Bets Today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.


We predict a close game between the Astros and Cubs on Wednesday, with each team having a 50% chance of winning..

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

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