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Astros vs. Red Sox prediction: Boston favored to win Sunday's MLB matchup [5/3/2026]
Get Houston Astros vs Boston Red Sox predictions for MLB Sunday.

MLB action continues on Sunday at 1:35 PM ET as the Houston Astros lock horns with the Boston Red Sox at Fenway Park.
Ranger Suarez (2-2, 3.09 ERA) will get the ball for the Red Sox, up against Cody Bolton (0-1, 5.79 ERA) for the Astros.
Based on updated simulation results, Dimers' proven MLB model projects the Red Sox as the most likely winner of the Astros vs. Red Sox game.
This article offers further insights into Sunday's matchup, including best bets and picks.
Astros vs. Red Sox prediction: Who will win and cover?
Our independent predictive model gives the Red Sox a 57% chance of defeating the Astros.
According to our model, the Astros (+1.5) have a 61% chance of covering the run line, while the 9-run over/under has a 51% chance of staying under.
Astros vs. Red Sox odds [5/3/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Astros | Red Sox |
|---|---|---|
| Run Line | +1.5 (-134) | -1.5 (+119) |
| Moneyline | +152 | -180 |
| Total | o9 (+100) | u9 (-120) |
All odds are correct at the time of publication and are subject to change.
Astros vs. Red Sox picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | -134 |
| Moneyline | Astros | +152 |
| Total | Over 9 | +100 |
According to our MLB best bets, the top play to make on this game is Astros +1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Red Sox game-day updates and essential details
Sunday's MLB action between the Red Sox and Astros at Fenway Park is scheduled to commence at 1:35 PM ET.
- Who: Houston Astros vs. Boston Red Sox
- Date: Sunday, May 3, 2026
- Time: 1:35 PM ET/10:35AM PT
- Venue: Fenway Park
Conclusion
We predict the Red Sox, with a 57% win probability, will likely beat the Astros in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
