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Holy Cross vs. Harvard prediction: Harvard favored to win men's college basketball matchup [12/20/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Holy Cross vs Harvard predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 2:00 PM ET as Holy Cross locks horns with Harvard in men's college basketball action at Lavietes Pavilion.
Based on updated simulations, Dimers' proven college basketball model predicts Harvard as the most likely winner of the Holy Cross vs. Harvard game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Holy Cross vs. Harvard prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Holy Cross and Harvard 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Harvard an 85% chance of defeating Holy Cross. Our predicted final score has Harvard winning 74-64.
According to our model, the bookmakers have got it right, and Holy Cross and Harvard each have a 50% chance of covering the spread, while the 136.5-point over/under has a 54% chance of going over.
Holy Cross vs. Harvard odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Holy Cross | Harvard |
|---|---|---|
| Spread | +10.5 (-115) | -10.5 (-102) |
| Moneyline | +440 | -600 |
| Total | o136.5 (-110) | u136.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Holy Cross vs. Harvard picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Harvard -10.5 | -102 |
| Moneyline | Harvard | -600 |
| Total | Over 136.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Over 136.5 total points.
Holy Cross vs. Harvard game-day updates and essential details
Saturday's men's college basketball matchup between Harvard and Holy Cross at Lavietes Pavilion is scheduled to begin at 2:00 PM ET.
- Who: Holy Cross vs. Harvard
- Date: Saturday, December 20, 2025
- Time: 2:00 PM ET/11:00AM PT
- Venue: Lavietes Pavilion
Conclusion
We predict Harvard, with an 85% win probability, will likely beat Holy Cross on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Holy Cross vs. Harvard insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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