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Hofstra vs. Syracuse prediction: Syracuse favored to win men's college basketball matchup [12/13/2025]

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Written by Dave Garofolo

Get Hofstra vs Syracuse predictions for college basketball Saturday.

Hofstra-Syracuse Predictions and Game Preview.
Hofstra vs. Syracuse men's college basketball prediction for Saturday, December 13, 2025.

Syracuse and Hofstra will meet in men's college basketball action at JMA Wireless Dome on Saturday, with tipoff at 4:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model projects Syracuse as the most likely winner of the Hofstra vs. Syracuse game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Hofstra vs. Syracuse prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Hofstra and Syracuse 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Syracuse an 83% chance of beating Hofstra. Our predicted final score has Syracuse winning 73-64.

According to our model, Syracuse (-8.5) has a 54% chance of covering the spread, while the over/under total of 138.5 points has a 52% chance of staying under.

 

Hofstra vs. Syracuse odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Hofstra Syracuse
Spread +8.5 (-102) -8.5 (-120)
Moneyline +410 -500
Total o138.5 (-110) u138.5 (-110)

All odds are correct at the time of publication and are subject to change.

Hofstra vs. Syracuse picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Syracuse -8.5 -120
Moneyline Syracuse -500
Total Under 138.5 -110

According to our men's college basketball best bets, the top play to make on this game is Syracuse to win.

 

Hofstra vs. Syracuse game-day updates and essential details

Saturday's men's college basketball matchup between Syracuse and Hofstra at JMA Wireless Dome is scheduled to start at 4:00PM ET.

  • Who: Hofstra vs. Syracuse
  • Date: Saturday, December 13, 2025
  • Time: 4:00PM ET/1:00PM PT
  • Venue: JMA Wireless Dome

Conclusion

We predict Syracuse, with an 83% win probability, will likely beat Hofstra on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Hofstra vs. Syracuse insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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