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Hofstra vs. Syracuse prediction: Syracuse favored to win men's college basketball matchup [12/13/2025]

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Written by Dave Garofolo

Get Hofstra vs Syracuse predictions for college basketball Saturday.

Hofstra-Syracuse Predictions and Game Preview.
Hofstra vs. Syracuse men's college basketball prediction for Saturday, December 13, 2025.

Syracuse will take on Hofstra in men's college basketball action at JMA Wireless Dome on Saturday, commencing at 4:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Syracuse as the most likely winner of the Hofstra vs. Syracuse game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Hofstra vs. Syracuse prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Hofstra and Syracuse 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Syracuse an 85% chance of beating Hofstra. Our predicted final score has Syracuse winning 74-63.

According to our model, Hofstra (+11.5) has a 54% chance of covering the spread, while the 139.5-point over/under has a 52% chance of staying under.

 

Hofstra vs. Syracuse odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Hofstra Syracuse
Spread +11.5 (-110) -11.5 (-108)
Moneyline +570 -700
Total o139.5 (-105) u139.5 (-112)

All odds are correct at the time of publication and are subject to change.

Hofstra vs. Syracuse picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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