Harvard vs. St. John's prediction: St. John's favored to win men's college basketball matchup [12/23/2025]

St. John's will face Harvard in men's college basketball action at Carnesecca Arena on Tuesday, beginning at 6:00 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts St. John's as the most likely winner of the Harvard vs. St. John's game.

This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Harvard vs. St. John's prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Harvard and St. John's 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives St. John's a 98% chance of beating Harvard. Our predicted final score has St. John's winning 87-60.

According to our model, St. John's (-25.5) has a 52% chance of covering the spread, while the 145.5-point over/under has a 54% chance of going over.

Harvard vs. St. John's odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Harvard vs. St. John's picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: