Guardians vs. Yankees Prediction and Odds - Apr 24, 2022

The New York Yankees and Cleveland Guardians lock horns in MLB at Yankee Stadium on Sunday, starting at 1:35PM ET.

The Yankees will have Gerrit Cole (0-0, 6.35 ERA) start, up against Aaron Civale (0-1, 6.14 ERA) for the Guardians.

Dimers' top betting picks for Guardians vs. Yankees, plus game predictions and best odds, are detailed in this article.

Who will win Guardians vs. Yankees?

Based on trusted machine learning and data, Dimers.com has simulated Sunday's Guardians-Yankees MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Yankees a 65% chance of winning against the Guardians.

More: Guardians vs. Yankees Simulated 10,000 Times

Guardians vs. Yankees Current Odds

• Run Line: Yankees -1.5 (+105), Guardians +1.5 (-120)
• Moneyline: Yankees -200, Guardians +185
• Total: Over/Under 7 (+110/-120)

Run Line, Moneyline and Over/Under

The Yankees are -1.5 favorites against the Guardians, with +105 at BetMGM the best odds currently available.

For the underdog Guardians (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at -120.

BetMGM currently has the best moneyline odds for the Yankees at -200. That means you can risk $200 to win $100, for a total payout of $300, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Guardians at +185, where you can put down $100 to profit $185, earning a total payout of $285, if they win.

The Over/Under for total runs scored is set at 7 with Caesars Sportsbook, which currently has the best odds for the Over at +110, while FanDuel Sportsbook currently has the best odds for the Under at -120.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 54% chance of covering the run line, while the 7-run Over/Under is a 53% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Guardians vs. Yankees

• Run Line: Guardians +1.5 @ -120 via DraftKings Sportsbook (54% probability)
• Moneyline: Guardians @ +185 via Caesars Sportsbook (0.2% edge)
• Total: Over 7 @ +110 via Caesars Sportsbook (53% probability) 🔥

Every time you see a 🔥, that means you've found one of our best free picks today across all sports.

Dimers' best bets are based on world-class simulations and wagering intelligence to serve you the best possible plays 24/7.

While the Yankees are more likely to win the game, according to DimersBOT, betting on the Guardians moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers is one of the keys to achieving long-term profitability as a bettor.

Guardians vs. Yankees Betting Guide

Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. NY Yankees, and click or tap on See Matchup for more.

Dimers has full coverage of Sunday's Guardians-Yankees matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this article for the latest betting analysis ahead of Guardians vs. Yankees on Sunday April 24, 2022.

Best Sportsbook Promo for Guardians vs. Yankees

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Guardians vs. Yankees 2022 Game Info

When do the Yankees play the Guardians?

• Date: Sunday April 24, 2022
• Time: 1:35PM ET / 10:35AM PT
• Venue: Yankee Stadium

Looking to join an online sportsbook and start betting on MLB? Check out the best sportsbook sign-up offers in your state.

Want more MLB predictions like this?

To get more MLB betting previews like you've just read for Guardians vs. Yankees, all you've gotta do is visit our MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the most comprehensive MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.