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Guardians vs. Tigers Prediction and Odds - May 29, 2022

The Detroit Tigers take on the Cleveland Guardians in MLB action at Comerica Park on Sunday, commencing at 1:40PM ET.
The Tigers will have Elvin Rodriguez (0-0, 9.39 ERA) start, while the Guardians will counter with Triston McKenzie (3-3, 2.70 ERA).
Dimers' best betting picks for Guardians vs. Tigers, plus game predictions and best odds, are featured below.
Today's Cleveland vs. Detroit betting preview is proudly sponsored by PointsBet, which has a 5x $100 Risk-Free Bets offer for new users.
Who will win Guardians vs. Tigers?
Based on cutting-edge machine learning and data, Dimers.com has simulated Sunday's Guardians-Tigers MLB game 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, gives the Guardians a 62% chance of defeating the Tigers.
More: Free Betting Analysis for Guardians vs. Tigers
Guardians vs. Tigers Odds
- Run Line: Tigers +1.5 (-120), Guardians -1.5 (+106)
- Moneyline: Tigers +150, Guardians -164
- Total: Over/Under 8 (-105/-105)
Run Line, Moneyline and Over/Under
The Tigers are currently +1.5 underdogs versus the Guardians, with -120 at BetMGM the best odds currently available.
For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on the market at +106.
Caesars Sportsbook currently has the best moneyline odds for the Tigers at +150. That means you can bet $100 to profit $150, earning a total payout of $250, if they win.
On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -164, where you can risk $164 to win $100, for a total payout of $264, if they come out on top.
The Over/Under is set at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -105, while PointsBet currently has the best odds for the Under at -105.
As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.
According to DimersBOT, the Tigers (+1.5) are a 52% chance of covering the run line, while the Over/Under total of 8 runs is a 55% chance of going Over.
More: Free Online Bet Tracker
Best Bets for Guardians vs. Tigers
- Run Line: Guardians -1.5 @ +106 via FanDuel Sportsbook
- Moneyline: Guardians @ -164 via FanDuel Sportsbook (62% probability)
- Total: Over 8 @ -105 via Caesars Sportsbook (55% probability)
Dimers' best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays 24/7.
Although the Tigers are more likely to cover the run line, our best bet of Guardians -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.
Guardians vs. Tigers Probabilities
Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. Detroit, and click or tap on See Matchup to reveal more.
Dimers has full coverage of Sunday's Guardians-Tigers matchup, including pregame predictions, free betting picks, and live scores.
Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis before Guardians vs. Tigers on Sunday May 29, 2022.
Risk-Free Bet for Guardians vs. Tigers
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Guardians vs. Tigers 2022 Game Info
Sunday's game between the Tigers and Guardians at Comerica Park is scheduled to start at 1:40PM ET.
- Who: Detroit Tigers vs. Cleveland Guardians
- Date: Sunday May 29, 2022
- Time: 1:40PM ET / 10:40AM PT
- Venue: Comerica Park
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