Guardians vs. Reds Prediction and Odds - Apr 12, 2022

The Cincinnati Reds face the Cleveland Guardians in MLB action at Great American Ball Park on Tuesday, commencing at 4:10PM EDT.

The Reds will have Tyler Mahle (1-0, 0.00 ERA) start, while the Guardians are going with Shane Bieber (0-0, 1.93 ERA).

Dimers' free betting picks for Guardians vs. Reds, plus game predictions and best odds, are featured in this article.

Who will win Guardians vs. Reds?

Using trusted machine learning and data, Dimers.com has simulated Tuesday's Guardians-Reds MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Reds a 51% chance of beating the Guardians.

More: Guardians vs. Reds Simulated 10,000 Times

Guardians vs. Reds Odds

• Run Line: Reds +1.5, Guardians -1.5
• Moneyline: Reds -110, Guardians +100
• Total: Over/Under 8

Run Line, Moneyline and Over/Under

The Reds are listed as +1.5 underdogs versus the Guardians, with -169 at Caesars Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +158.

Caesars Sportsbook currently has the best moneyline odds for the Reds at -110. That means you can risk $110 to win $100, for a total payout of $210, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Guardians at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under sits at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, check out all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 51% chance of covering the run line, while the 8-run Over/Under is a 53% chance of going Over.

More: Predictions for Every MLB Game

Best Bets for Guardians vs. Reds

• Run Line: Guardians -1.5 @ +158 via FanDuel Sportsbook (10.6% edge) 🔥
• Moneyline: Guardians @ +100 via FanDuel Sportsbook
• Total: Over 8 @ -110 via DraftKings Sportsbook (53% probability)

Any time you see a 🔥, that means it's one of Dimers' best bets today across any sport.

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays 24/7/365.

Although the Reds are more likely to cover the run line, our best bet of Guardians -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

And while the Reds are more likely to win the game, according to DimersBOT, taking the Guardians moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers.com is one of the keys to being profitable in the long run.

Guardians vs. Reds Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. Cincinnati, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Tuesday's Guardians-Reds matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this article for the latest betting analysis ahead of Guardians vs. Reds on Tuesday April 12, 2022.

Get a Risk-Free Bet for Guardians vs. Reds

Are you looking to bet on Cleveland vs. Cincinnati? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Tuesday's Guardians-Reds matchup.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Guardians vs. Reds. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Guardians vs. Reds 2022 Game Info

When do the Reds play the Guardians?

• Date: Tuesday April 12, 2022
• Time: 4:10PM EDT / 1:10PM PDT
• Venue: Great American Ball Park

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What other MLB games are on today?

The Guardians and Reds aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for each and every MLB matchup via our MLB Predictions page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out today!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.