Grambling State vs. Ohio State prediction: Ohio State favored to win men's college basketball matchup [12/23/2025]

Ohio State and Grambling State will lock horns in men's college basketball action at Value City Arena on Tuesday, with tipoff at 2:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Ohio State as the most likely winner of the Grambling State vs. Ohio State game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Grambling State vs. Ohio State prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Tuesday's NCAA basketball game between Grambling State and Ohio State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Ohio State a 98% chance of beating Grambling State. Our predicted final score has Ohio State winning 87-62.

According to our model, Grambling State (+27.5) has a 53% chance of covering the spread, while the 150.5-point over/under has a 53% chance of staying under.

Grambling State vs. Ohio State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Grambling State vs. Ohio State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: