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Gonzaga vs. San Diego prediction: Gonzaga favored to win men's college basketball matchup [12/30/2025]

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Written by Dave Garofolo

Get Gonzaga vs San Diego predictions for college basketball Tuesday.

Gonzaga-San Diego Predictions and Game Preview.
Gonzaga vs. San Diego men's college basketball prediction for Tuesday, December 30, 2025.

San Diego will face the favored Gonzaga in men's college basketball action at Jenny Craig Pavilion on Tuesday, commencing at 9:30 PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts Gonzaga as the most likely winner of the Gonzaga vs. San Diego game.

This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Gonzaga vs. San Diego prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Gonzaga and San Diego 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Gonzaga a 97% chance of beating San Diego. Our predicted final score has Gonzaga winning 90-67.

According to our model, San Diego (+29.5) has a 58% chance of covering the spread, while the 160.5-point over/under has a 53% chance of staying under.

 

Gonzaga vs. San Diego odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Gonzaga San Diego
Spread -29.5 (-110) +29.5 (-110)
Moneyline -6502 +5500
Total o160.5 (-110) u160.5 (-110)

All odds are correct at the time of publication and are subject to change.

Gonzaga vs. San Diego picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread San Diego +29.5 -110
Moneyline San Diego +5500
Total Under 160.5 -110

According to our men's college basketball best bets, the top play to make on this game is San Diego +29.5 at the spread.

 

Gonzaga vs. San Diego game-day updates and essential details

Tuesday's men's college basketball game between San Diego and Gonzaga at Jenny Craig Pavilion is scheduled to start at 9:30 PM ET.

  • Who: Gonzaga vs. San Diego
  • Date: Tuesday, December 30, 2025
  • Time: 9:30 PM ET/6:30PM PT
  • Venue: Jenny Craig Pavilion

Conclusion

We predict Gonzaga, with a 97% win probability, will likely beat San Diego on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Gonzaga vs. San Diego insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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