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Gonzaga vs. Kentucky prediction: Gonzaga favored to win men's college basketball matchup [12/5/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Gonzaga vs Kentucky predictions for college basketball Friday.
Kentucky will square off with the favored Gonzaga in men's college basketball action at Bridgestone Arena on Friday, starting at 7:00PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts Gonzaga as the most likely winner of the Gonzaga vs. Kentucky game.
This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.
Gonzaga vs. Kentucky prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Friday's NCAA basketball matchup between Gonzaga and Kentucky 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Gonzaga a 64% chance of defeating Kentucky. Our predicted final score has Gonzaga winning 80-76.
According to our model, Kentucky (+5.5) has a 58% chance of covering the spread, while the 158.5-point over/under has a 54% chance of staying under.
Gonzaga vs. Kentucky odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Gonzaga | Kentucky |
|---|---|---|
| Spread | -5.5 (-105) | +5.5 (-110) |
| Moneyline | -225 | +205 |
| Total | o158.5 (-115) | u158.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Gonzaga vs. Kentucky picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Kentucky +5.5 | -110 |
| Moneyline | Kentucky | +205 |
| Total | Under 158.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Kentucky +5.5 at the spread.
Gonzaga vs. Kentucky game-day updates and essential details
Friday's men's college basketball matchup between Kentucky and Gonzaga at Bridgestone Arena is scheduled to begin at 7:00PM ET.
- Who: Gonzaga vs. Kentucky
- Date: Friday, December 5, 2025
- Time: 7:00PM ET/4:00PM PT
- Venue: Bridgestone Arena
Conclusion
We predict Gonzaga, with a 64% win probability, will likely beat Kentucky on Friday.
AI and automation have enhanced this article to quickly deliver accurate Gonzaga vs. Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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