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Warriors vs. Lakers prediction: Golden State to win, Luka Doncic projected for 27 points on NBA Opening Night [10/21/2025]
Get Golden State Warriors vs Los Angeles Lakers predictions for NBA Tuesday.

The Los Angeles Lakers and Golden State Warriors will meet in NBA Opening Night action at Crypto.com Arena on Tuesday, with tipoff at 10:00PM ET.
Based on updated simulation results and today’s injury updates, Dimers' advanced NBA model predicts the Warriors as the most likely winner of today's game.
This prediction follows the latest NBA Injury Report, which suggests the Lakers lineup will feature players like Luka Doncic, Austin Reaves and Deandre Ayton, while the Warriors will rely on Stephen Curry, Jimmy Butler and Jonathan Kuminga.
LeBron James will miss the game though with the superstar out for this one.
For a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Warriors vs. Lakers predictions page.
Warriors vs. Lakers prediction: Who will win, cover the spread?
Using innovative machine learning and data, we have simulated the result of Tuesday's NBA matchup between the Warriors and Lakers 10,000 times as part of our NBA predictions coverage.
Our famous predictive model gives the Warriors a 58% chance of defeating the Lakers. Our predicted final score has the Warriors winning 114-112.
According to our model, the Lakers (+2.5) have a 52% chance of covering the spread, while the 227.5-point over/under has a 51% chance of staying under.
Warriors vs. Lakers odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Warriors | Lakers |
|---|---|---|
| Spread | -2.5 (-110) | +2.5 (-105) |
| Moneyline | -140 | +124 |
| Total | o227.5 (-105) | u227.5 (-110) |
All odds are correct at the time of publication and are subject to change.
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Warriors vs. Lakers picks and best bets
Our model's strongest edge in today's Warriors vs. Lakers matchup is on the total.
Our expert predictions, aligned with the latest odds, reveal the best NBA picks and NBA best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Warriors vs. Lakers player props
Looking for Golden State vs. LA Lakers NBA player props? We have crunched the numbers to project how each team's leading players will perform at Crypto.com Arena.
Stephen Curry is expected to lead the Warriors with 24 points, 4 rebounds and 6 assists, while Luka Doncic is projected to have 27 points, 7 rebounds and 7 assists for the Lakers.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.
Warriors vs. Lakers game-day updates and essential details
Tuesday's action between the Lakers and Warriors at Crypto.com Arena is scheduled to begin at 10:00PM ET.
- Who: Golden State Warriors vs. Los Angeles Lakers
- Date: Tuesday, October 21, 2025
- Time: 10:00PM ET/7:00PM PT
- Venue: Crypto.com Arena
Dimers' full preview of Tuesday's Warriors vs. Lakers matchup includes our prediction, picks and the latest betting odds.
Before making any Warriors vs. Lakers picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.
Conclusion
We predict the Warriors, with a 58% win probability, will likely beat the Lakers on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Warriors vs. Lakers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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