Giants vs. Mets Prediction and Odds - Apr 21, 2022

The New York Mets and San Francisco Giants clash in MLB at Citi Field on Thursday, starting at 1:10PM ET.

The Mets will have Carlos Carrasco (0-0, 0.84 ERA) start, pitting him against Anthony DeSclafani (0-0, 4.32 ERA) for the Giants.

Dimers' top betting picks for Giants vs. Mets, as well as game predictions and best odds, are detailed below.

Who will win Giants vs. Mets?

Using cutting-edge computer power and data, Dimers.com has simulated Thursday's Giants-Mets MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Mets a 58% chance of beating the Giants.

More: Giants vs. Mets Simulated 10,000 Times

Giants vs. Mets Odds

• Run Line: Mets -1.5 (+155), Giants +1.5 (-170)
• Moneyline: Mets -135, Giants +120
• Total: Over/Under 8 (-115/-104)

Run Line, Moneyline and Over/Under

The Mets are -1.5 favorites against the Giants, with +155 at FanDuel Sportsbook the best odds currently available.

For the underdog Giants (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -170.

PointsBet currently has the best moneyline odds for the Mets at -135, which means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Giants at +120, where you can put down $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under sits at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 61% chance of covering the run line, while the 8-run Over/Under is a 54% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Giants vs. Mets

• Run Line: Mets -1.5 @ +155 via FanDuel Sportsbook (0.1% edge)
• Moneyline: Mets @ -135 via PointsBet (58% probability)
• Total: Over 8 @ -115 via Caesars Sportsbook (54% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to help you make more informed investments with the legal sportsbooks in your state.

Although the Giants are more likely to cover the run line, our best bet of Mets -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Giants vs. Mets Probabilities

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. NY Mets, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Thursday's Giants-Mets matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so refresh this page for the latest betting analysis before Giants vs. Mets on Thursday April 21, 2022.

Best Sportsbook Promo for Giants vs. Mets

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Giants vs. Mets 2022 Game Info

When do the Mets play the Giants?

• Date: Thursday April 21, 2022
• Time: 1:10PM ET / 10:10AM PT
• Venue: Citi Field

Looking to join an online sportsbook and start betting on MLB? We've reviewed the best available welcome offers for each legal betting state.

What other MLB games are on today?

Now you've got the 411 on Giants vs. Mets, see the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.