Giants vs. Dodgers Prediction and Odds - May 4, 2022

The Los Angeles Dodgers and San Francisco Giants clash in MLB at Dodger Stadium on Wednesday, starting at 10:10PM ET.

The Dodgers will send Tony Gonsolin (1-0, 1.59 ERA) to the mound, while the Giants will counter with Alex Wood (2-1, 4.19 ERA).

Dimers' top betting picks for Giants vs. Dodgers, plus game predictions and best odds, are detailed in this article.

This San Francisco vs. LA Dodgers betting preview is sponsored by PointsBet, which has a tasty 5x $100 Risk-Free Bets promo for new users.

Who will win Giants vs. Dodgers?

Based on high-tech machine learning and data, Dimers.com has simulated Wednesday's Giants-Dodgers MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Dodgers a 58% chance of beating the Giants.

More: Giants vs. Dodgers Simulated 10K Times

Giants vs. Dodgers Game Odds

• Run Line: Dodgers -1.5 (+125), Giants +1.5 (-134)
• Moneyline: Dodgers -165, Giants +155
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Dodgers are -1.5 favorites versus the Giants, with +125 at BetMGM the best odds currently available.

For the underdog Giants (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -134.

BetMGM currently has the best moneyline odds for the Dodgers at -165, which means you can risk $165 to win $100, for a total payout of $265, if they get the W.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Giants at +155, where you can bet $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under is set at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 61% chance of covering the run line, while the 7.5-run Over/Under is a 51% chance of going Under.

More: Today's Best Bets for All Major Sports

Best Bets for Giants vs. Dodgers

• Run Line: Giants +1.5 @ -134 via FanDuel Sportsbook (61% probability)
• Moneyline: Giants @ +155 via Caesars Sportsbook (2.5% edge)
• Total: Under 7.5 @ -105 via PointsBet (51% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in the United States.

While the Dodgers are more likely to win the game, according to DimersBOT, taking the Giants moneyline is the best option because of the 2.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is crucial to being profitable in the long run.

Giants vs. Dodgers Betting Guide

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. LA Dodgers, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Giants-Dodgers matchup, including pregame predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this article for the latest betting insights before Giants vs. Dodgers on Wednesday May 4, 2022.

Best Betting Promo for Giants vs. Dodgers

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Giants vs. Dodgers 2022 Game Info

When do the Dodgers play the Giants?

• Date: Wednesday May 4, 2022
• Time: 10:10PM ET / 7:10PM PT
• Venue: Dodger Stadium

Ready to join an online sportsbook and start betting on MLB now? We've listed the best available sign-up offers in each and every legal betting state.

What other MLB games are on today?

The Giants and Dodgers aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB matchup in our MLB Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out today!

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.