Giants vs. Cardinals Prediction and Odds - May 14, 2022

The St Louis Cardinals and San Francisco Giants lock horns in MLB at Busch Stadium on Saturday, starting at 2:15PM ET.

The Cardinals will have Dakota Hudson (2-2, 3.56 ERA) start, pitting him against Jakob Junis (1-0, 1.20 ERA) for the Giants.

Dimers' free betting picks for Giants vs. Cardinals, plus game predictions and best odds, are featured below.

Today's San Francisco vs. St Louis betting preview is presented by PointsBet, which has an outstanding 5x $100 Risk-Free Bets promo for new customers.

Who will win Giants vs. Cardinals?

Using state-of-the-art machine learning and data, Dimers.com has simulated Saturday's Giants-Cardinals MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Cardinals a 51% chance of defeating the Giants.

More: Free Betting Analysis for Giants vs. Cardinals

Giants vs. Cardinals Odds

• Run Line: Cardinals +1.5 (-155), Giants -1.5 (+135)
• Moneyline: Cardinals +105, Giants -120
• Total: Over/Under 8.5 (-118/+105)

Run Line, Moneyline and Over/Under

The Cardinals are +1.5 underdogs versus the Giants, with -155 at DraftKings Sportsbook the best odds currently available.

For the favored Giants (-1.5) to cover the run line, BetMGM has the best odds currently on the market at +135.

DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +105. That means you can throw down $100 to profit $105, earning a total payout of $205, if they win.

Meanwhile, BetMGM currently has the best moneyline odds for the Giants at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under is set at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, while PointsBet currently has the best odds for the Under at +105.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 63% chance of covering the run line, while the Over/Under total of 8.5 runs is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Giants vs. Cardinals

• Run Line: Cardinals +1.5 @ -155 via DraftKings Sportsbook (63% probability)
• Moneyline: Cardinals @ +105 via DraftKings Sportsbook (51% probability)
• Total: Under 8.5 @ +105 via PointsBet

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays every time.

Despite the Over being more likely to hit on this occasion, Under 8.5 is our best bet on account of the better odds (+105) that are available from PointsBet.

Giants vs. Cardinals Betting Guide

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. St Louis, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Saturday's Giants-Cardinals matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates often, so refresh this page for the latest betting insights ahead of Giants vs. Cardinals on Saturday May 14, 2022.

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Giants vs. Cardinals 2022 Game Info

Saturday's matchup between the Cardinals and Giants at Busch Stadium is scheduled to commence at 2:15PM ET.

• Date: Saturday May 14, 2022
• Time: 2:15PM ET / 11:15AM PT
• Venue: Busch Stadium

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What other MLB games are on today?

The Giants and Cardinals aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single MLB game via our MLB Predictions page.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.