Giants vs. Cardinals Prediction and Odds - May 13, 2022

The St Louis Cardinals and San Francisco Giants clash in MLB at Busch Stadium on Friday, starting at 8:15PM ET.

Jordan Hicks (1-2, 3.78 ERA) will be on the bump for the Cardinals, while the Giants will counter with Logan Webb (4-1, 3.82 ERA).

Dimers' top betting picks for Giants vs. Cardinals, plus game predictions and best odds, are detailed in this article.

This San Francisco vs. St Louis betting analysis is brought to you by PointsBet, which has a 5x $100 Risk-Free Bets offer for new customers.

Who will win Giants vs. Cardinals?

Using trusted computer power and data, Dimers.com has simulated Friday's Giants-Cardinals MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Cardinals a 53% chance of beating the Giants.

More: Giants vs. Cardinals Simulated 10K Times

Giants vs. Cardinals Current Odds

• Run Line: Cardinals +1.5 (-155), Giants -1.5 (+140)
• Moneyline: Cardinals +105, Giants -120
• Total: Over/Under 7.5 (-110/-104)

Run Line, Moneyline and Over/Under

The Cardinals are +1.5 underdogs versus the Giants, with -155 at DraftKings Sportsbook the best odds currently available.

For the favored Giants (-1.5) to cover the run line, PointsBet has the best odds currently on offer at +140.

DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +105. That means you can bet $100 to profit $105, earning a total payout of $205, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Giants at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under sits at 7.5 with PointsBet, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 64% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Giants vs. Cardinals

• Run Line: Cardinals +1.5 @ -155 via DraftKings Sportsbook (64% probability)
• Moneyline: Cardinals @ +105 via DraftKings Sportsbook (53% probability)
• Total: Over 7.5 @ -110 via PointsBet (52% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in America.

Giants vs. Cardinals Probabilities

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. St Louis, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's Giants-Cardinals matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates often, so refresh this article for any changes to our betting analysis before Giants vs. Cardinals on Friday May 13, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Giants vs. Cardinals 2022 Game Info

Friday's matchup between the Cardinals and Giants at Busch Stadium is scheduled to start at 8:15PM ET.

• Date: Friday May 13, 2022
• Time: 8:15PM ET / 5:15PM PT
• Venue: Busch Stadium

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What other MLB games are on today?

Now you've got the 411 on Giants vs. Cardinals, take a look at the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.