Eastern Illinois vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [12/14/2025]

Iowa State and Eastern Illinois are scheduled to meet in men's college basketball action at James H. Hilton Coliseum on Sunday, starting at 1:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Iowa State as the most likely winner of the Eastern Illinois vs. Iowa State game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Eastern Illinois vs. Iowa State prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's NCAA basketball game between Eastern Illinois and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 99% chance of defeating Eastern Illinois. Our predicted final score has Iowa State winning 89-56.

According to our model, Eastern Illinois (+41.5) has a 60% chance of covering the spread, while the over/under total of 144.5 points has a 53% chance of going over.

Eastern Illinois vs. Iowa State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Eastern Illinois vs. Iowa State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: