Duke vs. Virginia CBB Predictions and Odds - Feb 23, 2022

Virginia and Duke clash in College Basketball action at John Paul Jones Arena on Wednesday, with tipoff at 7:00PM EST.

Dimers' free betting picks for Duke vs. Virginia, as well as our score prediction and best odds, are detailed in this article.

Who will win Duke vs. Virginia?

Based on state-of-the-art computer power and data, Dimers.com has simulated Wednesday's Duke-Virginia NCAA Basketball game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives Duke a 69% chance of defeating Virginia.

MORE: Duke vs. Virginia Simulated 10K Times

Point Spread, Moneyline and Over/Under

Virginia is currently the +5.5 underdog against Duke, with -110 at PointsBet the best odds currently available.

For the favored Duke (-5.5) to cover the spread, PointsBet also has the best odds currently on offer at -110.

PointsBet currently has the best moneyline odds for Virginia at +205. That means you can throw down $100 to profit $205, earning a total payout of $305, if it wins.

Meanwhile, BetMGM currently has the best moneyline odds for Duke at -225, where you can risk $225 to win $100, for a total payout of $325, if it comes out on top.

The Over/Under for total points scored is set at 129.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all the sportsbooks that are available in your state for the best College Basketball odds and lines.

According to DimersBOT, Virginia (+5.5) is a 57% chance of covering the spread, while the 129.5-point Over/Under is a 52% chance of going Over.

MORE: Best Bets Today for All Major College Sports

Best Bets for Duke vs. Virginia

• Spread: Virginia +5.5 at -110 with PointsBet (57% probability) 🔥
• Moneyline: Duke at -225 with BetMGM (69% probability)
• Over/Under: Over 129.5 at -110 with PointsBet (52% probability)

If you see a 🔥, you know it's one of Dimers' best free picks of the day across any sport.

Dimers' best bets are based on world-class simulations and betting intelligence to help you make more informed decisions.

Duke vs. Virginia Score Prediction

Dimers.com's predicted final score for Duke vs. Virginia at John Paul Jones Arena this Wednesday has Duke winning 67-63.

Use our interactive widget below to see up-to-date Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Duke-Virginia matchup, including pre-game predictions, free picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this article for the latest betting analysis before Duke vs. Virginia on Wednesday February 23, 2022.

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Duke vs. Virginia 2022 CBB Game Info

When does Virginia play Duke in College Basketball?

• Date: Wednesday February 23, 2022
• Time: 7:00PM EST / 4:00PM PST
• Venue: John Paul Jones Arena

Ready to join an online sportsbook and start betting on College Basketball? We've reviewed the best available sign-up offers for each legal betting state.

What CBB games are on tonight?

Now you've got the 411 on Duke vs. Virginia, get the latest betting analysis for all upcoming NCAA Basketball games in Dimers' College Basketball Bet Hub. There you can find probabilities and odds, plus our best bets for each and every CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!