Duke vs. Syracuse CBB Predictions and Odds - Feb 26, 2022

College Basketball action continues on Saturday at 6:00PM EST as the favored Duke squares off with Syracuse at Carrier Dome.

Dimers' top betting picks for Duke vs. Syracuse, as well as our score prediction and best odds, are featured in this article.

Who will win Duke vs. Syracuse?

Using high-tech computer power and data, Dimers.com has simulated Saturday's Duke-Syracuse NCAA Basketball matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives Duke a 73% chance of beating Syracuse.

MORE: Free Betting Guide for Duke vs. Syracuse

Point Spread, Moneyline and Over/Under

Syracuse is the +7.5 underdog against Duke, with -110 at BetMGM the best odds currently available.

For the favored Duke (-7.5) to cover the spread, PointsBet has the best odds currently on offer at -105.

DraftKings Sportsbook currently has the best moneyline odds for Syracuse at +270, which means you can bet $100 to profit $270, earning a total payout of $370, if it wins.

On the other hand, PointsBet currently has the best moneyline odds for Duke at -320, where you can risk $320 to win $100, for a total payout of $420, if it comes out on top.

The Over/Under sits at 151 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best College Basketball odds and lines.

According to DimersBOT, Syracuse (+7.5) is a 56% chance of covering the spread, while the Over/Under total of 151 points is a 57% chance of going Under.

MORE: Live Win Probabilities for All Major College Sports

Best Bets for Duke vs. Syracuse

• Spread: Syracuse +7.5 at -110 with BetMGM (56% probability)
• Moneyline: Syracuse at +270 with DraftKings Sportsbook (1.2% edge)
• Over/Under: Under 151 at -110 with DraftKings Sportsbook (57% probability) 🔥

When you see a 🔥, that means you've found one of Dimers' best free picks of the day across any sport.

Dimers' best bets are based on complex simulations and wagering intelligence to help you make more informed decisions.

While Duke is more likely to win the game, according to DimersBOT, betting on Syracuse moneyline is the best option because of the 1.2% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers.com is pivotal to being profitable in the long run.

Duke vs. Syracuse Score Prediction

Dimers.com's predicted final score for Duke vs. Syracuse at Carrier Dome this Saturday has Duke winning 77-71.

Use our interactive widget below to view the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Saturday's Duke-Syracuse matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep checking this page for any changes to our betting insights ahead of Duke vs. Syracuse on Saturday February 26, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Duke vs. Syracuse 2022 CBB Game Info

When does Syracuse play Duke in College Basketball?

• Date: Saturday February 26, 2022
• Time: 6:00PM EST / 3:00PM PST
• Venue: Carrier Dome

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Want more CBB previews like this?

To get more NCAA Basketball betting predictions like you've just read for Duke vs. Syracuse, all you've gotta do is visit Dimers' College Basketball Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the best CBB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.