Duke vs. Louisville CBB Predictions and Odds - Jan 29, 2022

Louisville and Duke meet in College Basketball action at KFC Yum! Center on Saturday, with tipoff at 12:00PM EST.

Dimers' free betting picks for Duke vs. Louisville, plus our score prediction and best odds, are detailed below.

Who will win Duke vs. Louisville?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Saturday's Duke-Louisville NCAA Basketball matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives Duke a 69% chance of winning against Louisville.

MORE: Duke vs. Louisville Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

Louisville is the +7 underdog against Duke, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Duke (-7) to cover the spread, DraftKings Sportsbook also has the best odds currently on offer at -110.

DraftKings Sportsbook currently has the best moneyline odds for Louisville at +240, which means you can bet $100 to profit $240, earning a total payout of $340, if it wins.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Duke at -275, where you can risk $275 to win $100, for a total payout of $375, if it comes out on top.

The Over/Under is set at 142 with PointsBet, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -102.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, Louisville (+7) is a 65% chance of covering the spread, while the 142-point Over/Under is considered an equal 50-50 chance of hitting.

MORE: Today's Best Bets for All Major College Sports

Best Bets for Duke vs. Louisville

• Spread: Louisville +7 at -110 with DraftKings Sportsbook (65% probability) 🔥
• Moneyline: Louisville at +240 with DraftKings Sportsbook (3.4% edge)
• Over/Under: Under 142 at -102 with FanDuel Sportsbook (50% probability)

When you see a 🔥, that means you've found one of our best bets of the day across all sports.

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays 24/7.

While Duke is more likely to win the game, according to DimersBOT, taking Louisville moneyline is the best option due to the 3.4% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is pivotal to achieving long-term profitability as a sports bettor.

Duke vs. Louisville Score Prediction

Dimers.com's predicted final score for Duke vs. Louisville at KFC Yum! Center this Saturday has Duke winning 73-68.

Use our dynamic widget below to explore up-to-date Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Duke-Louisville matchup, including pre-game predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this page for the latest betting analysis before Duke vs. Louisville on Saturday January 29, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Duke vs. Louisville 2022 CBB Game Info

When does Louisville play Duke in College Basketball?

• Date: Saturday January 29, 2022
• Time: 12:00PM EST / 9:00AM PST
• Venue: KFC Yum! Center

Want to join an online sportsbook and start betting on College Basketball? Check out the top sports betting sign-up offers in your state.

What other CBB games are on today?

Duke and Louisville aren't the only two NCAA Basketball teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single CBB game in our College Basketball Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out today!