Dodgers vs. Padres Prediction and Odds - Apr 22, 2022

The San Diego Padres square off with the Los Angeles Dodgers in MLB action at PETCO Park on Friday, starting at 9:40PM ET.

Nick Martinez (0-1, 4.50 ERA) will be on the bump for the Padres, while the Dodgers are going with Julio Urías (0-1, 3.86 ERA).

Dimers' free betting picks for Dodgers vs. Padres, plus game predictions and best odds, are featured in this article.

Who will win Dodgers vs. Padres?

Based on high-tech computer power and data, Dimers.com has simulated Friday's Dodgers-Padres MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently can't split the two teams, giving both the Dodgers and Padres a 50% chance of winning the game.

More: Dodgers vs. Padres Simulated 10,000 Times

Dodgers vs. Padres Current Odds

• Run Line: Padres +1.5 (-125), Dodgers -1.5 (+110)
• Moneyline: Padres +142, Dodgers -155
• Total: Over/Under 8 (-110/+100)

Run Line, Moneyline and Over/Under

The Padres are +1.5 underdogs versus the Dodgers, with -125 at DraftKings Sportsbook the best odds currently available.

For the favored Dodgers (-1.5) to cover the run line, BetMGM has the best odds currently on the market at +110.

FanDuel Sportsbook currently has the best moneyline odds for the Padres at +142, which means you can throw down $100 to profit $142, earning a total payout of $242, if they win.

Meanwhile, BetMGM currently has the best moneyline odds for the Dodgers at -155, where you can risk $155 to win $100, for a total payout of $255, if they come out on top.

The Over/Under for total runs scored is set at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Padres (+1.5) are a 58% chance of covering the run line, while the Over/Under total of 8 runs is a 53% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Dodgers vs. Padres

• Run Line: Padres +1.5 @ -125 via DraftKings Sportsbook (58% probability)
• Moneyline: Padres @ +142 via FanDuel Sportsbook (50% probability) 🔥
• Total: Over 8 @ -110 via Caesars Sportsbook (53% probability)

Any time you see a 🔥, that means you've found one of Dimers' best free picks of the day across all major pro and college sports.

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in America.

Dodgers vs. Padres Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for LA Dodgers vs. San Diego, and click or tap on See Matchup for more.

Dimers has full coverage of Friday's Dodgers-Padres matchup, including pregame predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this page for the latest betting insights before Dodgers vs. Padres on Friday April 22, 2022.

Risk-Free Bet for Dodgers vs. Padres

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Dodgers vs. Padres 2022 Game Info

When do the Padres play the Dodgers?

• Date: Friday April 22, 2022
• Time: 9:40PM ET / 6:40PM PT
• Venue: PETCO Park

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Want more MLB previews like this?

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We use the power of predictive analytics to find value in the markets so we can publish the best MLB betting previews available. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.