DePaul vs. Villanova CBB Predictions and Odds - Jan 25, 2022

Villanova and DePaul clash in College Basketball action at The William B. Finneran Pavilion on Tuesday, with tipoff at 7:00PM EST.

Dimers' top betting picks for DePaul vs. Villanova, plus game predictions and best odds, are featured in this article.

Who will win DePaul vs. Villanova?

Based on cutting-edge computer power and data, Dimers.com has simulated Tuesday's DePaul-Villanova NCAA Basketball game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives Villanova a 92% chance of getting the W against DePaul.

MORE: DePaul vs. Villanova Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

Villanova is the -17.5 favorite against DePaul, with -110 at PointsBet the best odds currently available.

For the underdog DePaul (+17.5) to cover the spread, PointsBet also has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for Villanova at -2500. That means you can risk $2,500 to win $100, for a total payout of $2,600, if it gets the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for DePaul at +1400, where you can bet $100 to profit $1,400, earning a total payout of $1,500, if it wins.

The Over/Under is set at 133.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, DePaul (+17.5) is a 59% chance of covering the spread, while the 133.5-point Over/Under is a 53% chance of going Over.

MORE: Live Scores for All Major College Sports

Best Bets for DePaul vs. Villanova

• Spread: DePaul +17.5 at -110 with PointsBet (59% probability) 🔥
• Moneyline: DePaul at +1400 with DraftKings Sportsbook (1.6% edge)
• Over/Under: Over 133.5 at -110 with PointsBet (53% probability)

If you see a 🔥, that means you've found one of our best free picks of the day across all sports.

Dimers' best bets are based on world-class simulations and wagering intelligence to bring you the best possible plays 24/7.

While Villanova is more likely to win the game, according to DimersBOT, betting on DePaul moneyline is the best option because of the 1.6% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers.com is one of the keys to achieving long-term profitability.

DePaul vs. Villanova Score Prediction

Dimers.com's predicted final score for DePaul vs. Villanova at The William B. Finneran Pavilion on Tuesday has Villanova winning 74-60.

Use our dynamic widget below to explore up-to-date Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Tuesday's DePaul-Villanova matchup, including pre-game predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis ahead of DePaul vs. Villanova on Tuesday January 25, 2022.

Risk-Free Bet for DePaul vs. Villanova

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

DePaul vs. Villanova 2022 CBB Game Info

When does Villanova play DePaul in College Basketball?

• Date: Tuesday January 25, 2022
• Time: 7:00PM EST / 4:00PM PST
• Venue: The William B. Finneran Pavilion

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What CBB games are on tonight?

Now you've got the 411 on DePaul vs. Villanova, check out the latest betting predictions for all upcoming NCAA Basketball games in our College Basketball Bet Hub. There you can find probabilities and odds, plus our best bets for every single CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!