DePaul vs. St. John's CBB Predictions and Odds - Jan 5, 2022

St. John's squares off with DePaul in College Basketball action at Carnesecca Arena on Wednesday, beginning at 6:30PM EST.

Dimers' top betting picks for DePaul vs. St. John's, plus game predictions and best odds, are featured in this article.

Who will win DePaul vs. St. John's?

Based on trusted computer power and data, Dimers.com has simulated Wednesday's DePaul-St. John's NCAA Basketball game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives St. John's a 71% chance of defeating DePaul.

MORE: DePaul vs. St. John's Simulated 10,000 Times

Point Spread, Moneyline and Over/Under

St. John's is currently the -4.5 favorite versus DePaul, with -115 at BetMGM the best odds available.

For the underdog DePaul (+4.5) to cover the spread, BetMGM also has the best odds on offer at -105.

BetMGM has the best moneyline odds for St. John's at -200. That means you can risk $200 to win $100, for a total payout of $300, if it gets the W.

Elsewhere, FanDuel Sportsbook has the best moneyline odds for DePaul at +188, where you can bet $100 to profit $188, earning a total payout of $288, if it wins.

The Over/Under is set at 153.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all the online sportsbooks that are available in your state for the best College Basketball odds and lines.

According to DimersBOT, St. John's (-4.5) is a 62% chance of covering the spread, while the Over/Under total of 153.5 points is a 54% chance of going Under.

MORE: Best Bets for Every CBB Game

Best Bets for DePaul vs. St. John's

• Spread: St. John's -4.5 at -115 with BetMGM (62% probability) 🔥
• Moneyline: St. John's Win at -200 with BetMGM (71% probability) 🔥
• Over/Under: Under 153.5 at -110 with BetMGM (54% probability)

Every time you see a 🔥, you know it's one of Dimers' best bets of the day across any sport.

DePaul vs. St. John's Score Prediction

Dimers.com's predicted final score for DePaul vs. St. John's at Carnesecca Arena this Wednesday has St. John's winning 78-72.

Use our interactive widget below to explore the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's DePaul-St. John's matchup, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis ahead of DePaul vs. St. John's on Wednesday January 5, 2022.

Risk-Free Bet for DePaul vs. St. John's

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

DePaul vs. St. John's 2022 CBB Game Info

When does St. John's play DePaul in College Basketball?

• Date: Wednesday January 5, 2022
• Time: 6:30PM EST / 3:30PM PST
• Venue: Carnesecca Arena

Looking to join an online sportsbook and start betting on College Basketball today? Check out the top sports betting offers in your state.

Want more CBB analysis like this?

To get more NCAA Basketball betting predictions like you've just read for DePaul vs. St. John's, all you've gotta do is visit our College Basketball Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the best CBB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.