DePaul vs. St. John's CBB Prediction and Odds - Dec 7, 2022

St. John's and DePaul lock horns in College Basketball action at Carnesecca Arena on Wednesday, starting at 6:30PM ET.

Dimers' top betting picks for DePaul vs. St. John's, plus game predictions and betting odds, are detailed below.

Who will win DePaul vs. St. John's?

Based on cutting-edge machine learning and data, Dimers.com has simulated Wednesday's DePaul-St. John's College Basketball game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives St. John's a 77% chance of beating DePaul.

More: DePaul vs. St. John's Simulated 10K Times

DePaul vs. St. John's Game Odds

• Spread: St. John's -9.5 (-105), DePaul +9.5 (-110)
• Moneyline: St. John's -420, DePaul +385
• Total: Over/Under 157.5 (-110/-110)

Point Spread, Moneyline and Over/Under

St. John's is the -9.5 favorite versus DePaul, with -105 at BetMGM the best odds currently available.

For the underdog DePaul (+9.5) to cover the spread, PointsBet has the best odds currently on offer at -110.

PointsBet currently has the best moneyline odds for St. John's at -420. That means you can risk $420 to win $100, for a total payout of $520, if it gets the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for DePaul at +385, where you can bet $100 to profit $385, earning a total payout of $485, if it wins.

The Over/Under for total points scored is set at 157.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, DePaul (+9.5) is a 60% chance of covering the spread, while the 157.5-point Over/Under is a 51% chance of going Under.

More: Live Win Probabilities for All Major College Sports

Best Bets for DePaul vs. St. John's

• Spread: DePaul +9.5 @ -110 via PointsBet (60% probability) 🔥
• Moneyline: DePaul @ +385 via FanDuel Sportsbook (2.5% edge)
• Total: Under 157.5 @ -110 via PointsBet (51% probability)

Every time you see a 🔥, that means it's one of our best free picks of the day across all sports.

Our best bets are based on detailed modeling and gambling expertise to help you make better investments with the legal sportsbooks in the USA.

While St. John's is more likely to win the game, according to DimersBOT, taking DePaul moneyline is the best option because of the 2.5% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to achieving long-term profitability as a bettor.

DePaul vs. St. John's Prediction

Dimers.com's predicted final score for DePaul vs. St. John's at Carnesecca Arena on Wednesday has St. John's winning 82-75.

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's DePaul-St. John's matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this article for the latest betting insights ahead of DePaul vs. St. John's on Wednesday December 7, 2022.

DePaul vs. St. John's 2022 CBB Game Info

Wednesday's action between St. John's and DePaul in College Basketball at Carnesecca Arena is scheduled to begin at 6:30PM ET.

• Who: DePaul vs. St. John's
• Date: Wednesday December 7, 2022
• Time: 6:30PM ET / 3:30PM PT
• Venue: Carnesecca Arena

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What other College Basketball games are on tonight?

Now you've got the 411 on DePaul vs. St. John's, check out the latest betting analysis for all upcoming NCAA Basketball games in Dimers' College Basketball Bet Hub. There you can find probabilities and odds, and our best bets for every single CBB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' NCAA Basketball Futures page is our in-house approach to determining who will win March Madness 2022, with our data-led probabilities paired with the best odds available.