D-Backs vs. Nationals Prediction and Odds - Apr 21, 2022

The Washington Nationals square off with the Arizona D-Backs in MLB action at Nationals Park on Thursday, commencing at 4:05PM ET.

Josh Rogers (1-1, 3.72 ERA) will be on the bump for the Nationals, while the D-Backs are going with Zach Davies (0-1, 5.79 ERA).

Dimers' top betting picks for D-Backs vs. Nationals, as well as game predictions and best odds, are detailed below.

Who will win D-Backs vs. Nationals?

Using advanced computer power and data, Dimers.com has simulated Thursday's D-Backs-Nationals MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the Nationals a 54% chance of getting the W against the D-Backs.

More: Full Betting Analysis for D-Backs vs. Nationals

D-Backs vs. Nationals Game Odds

• Run Line: Nationals -1.5 (+155), D-Backs +1.5 (-169)
• Moneyline: Nationals -130, D-Backs +114
• Total: Over/Under 9 (-110/+100)

Run Line, Moneyline and Over/Under

The Nationals are -1.5 favorites versus the D-Backs, with +155 at FanDuel Sportsbook the best odds currently available.

For the underdog D-Backs (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -169.

Caesars Sportsbook currently has the best moneyline odds for the Nationals at -130, which means you can risk $130 to win $100, for a total payout of $230, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the D-Backs at +114, where you can bet $100 to profit $114, earning a total payout of $214, if they win.

The Over/Under sits at 9 with BetMGM, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the D-Backs (+1.5) are a 63% chance of covering the run line, while the 9-run Over/Under is a 53% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for D-Backs vs. Nationals

• Run Line: D-Backs +1.5 @ -169 via Caesars Sportsbook (63% probability)
• Moneyline: D-Backs @ +114 via FanDuel Sportsbook
• Total: Over 9 @ -110 via BetMGM (53% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays 24/7/365.

While the Nationals are more likely to win the game, according to DimersBOT, taking the D-Backs moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers.com is one of the keys to being a profitable sports bettor in the long run.

D-Backs vs. Nationals Probabilities

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Arizona vs. Washington, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Thursday's D-Backs-Nationals matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting insights before D-Backs vs. Nationals on Thursday April 21, 2022.

Best Sportsbook Promo for D-Backs vs. Nationals

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

D-Backs vs. Nationals 2022 Game Info

When do the Nationals play the D-Backs?

• Date: Thursday April 21, 2022
• Time: 4:05PM ET / 1:05PM PT
• Venue: Nationals Park

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What MLB games are on today?

Now you've got the 411 on D-Backs vs. Nationals, check out the latest betting predictions for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.