D-Backs vs. Cardinals Prediction and Odds - Apr 28, 2022

The St Louis Cardinals and Arizona D-Backs clash in MLB at Busch Stadium on Thursday, starting at 7:45PM ET.

The Cardinals will send Dakota Hudson (1-1, 3.95 ERA) to the mound, up against Humberto Castellanos (1-0, 3.00 ERA) for the D-Backs.

Dimers' best betting picks for D-Backs vs. Cardinals, as well as game predictions and best odds, are featured in this article.

Who will win D-Backs vs. Cardinals?

Based on cutting-edge computer power and data, Dimers.com has simulated Thursday's D-Backs-Cardinals MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Cardinals a 62% chance of winning against the D-Backs.

More: Free Betting Guide for D-Backs vs. Cardinals

D-Backs vs. Cardinals Current Odds

• Run Line: Cardinals -1.5 (+125), D-Backs +1.5 (-137)
• Moneyline: Cardinals -170, D-Backs +155
• Total: Over/Under 7.5 (+100/-115)

Run Line, Moneyline and Over/Under

The Cardinals are currently -1.5 favorites versus the D-Backs, with +125 at PointsBet the best odds currently available.

For the underdog D-Backs (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -137.

DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at -170, which means you can risk $170 to win $100, for a total payout of $270, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the D-Backs at +155, where you can bet $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under sits at 7.5 with BetMGM, which currently has the best odds for the Over at +100, while PointsBet currently has the best odds for the Under at -115.

As always, check out all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the D-Backs (+1.5) are a 56% chance of covering the run line, while the 7.5-run Over/Under is a 53% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for D-Backs vs. Cardinals

• Run Line: Cardinals -1.5 @ +125 via PointsBet
• Moneyline: Cardinals @ -170 via DraftKings Sportsbook (62% probability)
• Total: Over 7.5 @ +100 via BetMGM (53% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to bring you the best possible plays every day of the year.

Although the D-Backs are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

D-Backs vs. Cardinals Betting Guide

Use our interactive widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Arizona vs. St Louis, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's D-Backs-Cardinals matchup, including pregame predictions, top betting picks, and live scores.

Don't forget, DimersBOT updates regularly, so keep checking this article for the latest betting insights ahead of D-Backs vs. Cardinals on Thursday April 28, 2022.

Best Sportsbook Offer for D-Backs vs. Cardinals

Do you want to bet on Arizona vs. St Louis? Join FanDuel Sportsbook now and get a risk-free first bet up to $1,000, which you can use on Thursday's D-Backs-Cardinals matchup.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1K on D-Backs vs. Cardinals. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

D-Backs vs. Cardinals 2022 Game Info

When do the Cardinals play the D-Backs?

• Date: Thursday April 28, 2022
• Time: 7:45PM ET / 4:45PM PT
• Venue: Busch Stadium

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What MLB games are on today?

The D-Backs and Cardinals aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single MLB game via our MLB Predictions page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out today!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.