Daniil Medvedev vs. Reilly Opelka Prediction, Odds, Picks for ATP Libema Open 2025

Daniil Medvedev and Reilly Opelka will lock horns in the quarterfinals of the ATP Libema Open event on Friday.

Based on updated simulations, Dimers' proven tennis model (see Dimers Pro for full access) projects Daniil Medvedev as the most likely winner of the match.

"Employing the latest data, we simulated Friday's Medvedev-Opelka match 10,000 times," said Dimers data analyst Greg Butyn.

"After computing the latest updates and thousands of other inputs, we predict Daniil Medvedev's chance of winning is 71%, while Reilly Opelka's is 29%."

For a closer look at Friday's match, including best bets and picks, visit our interactive Medvedev vs. Opelka predictions page.

Medvedev vs. Opelka Prediction: Who Will Win and Advance to the Semifinals?

Using powerful machine learning and data, we have simulated the outcome of Friday's Medvedev-Opelka men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model currently gives Medvedev a 71% chance of beating Opelka at the ATP Libema Open tournament.

Additionally, Medvedev has a 66% chance of winning the first set, according to our model.

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Daniil Medvedev vs. Reilly Opelka Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Medvedev	Opelka
Moneyline	-357	+275
First Set	-250	+200

All odds are correct at the time of publication and are subject to change.

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Medvedev vs. Opelka Picks and Best Bets

Our model's biggest edge in today's Medvedev vs. Opelka match is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Medvedev vs. Opelka Updates and Essential Details

The ATP Libema Open match between Daniil Medvedev and Reilly Opelka is scheduled to commence on Friday at 9:10AM ET.

• Who: Daniil Medvedev vs. Reilly Opelka
• Date: Friday, June 13, 2025
• Approx. Time: 9:10AM ET/6:10AM PT
• Tournament: ATP S-Hertogenbosch, Netherlands Men's Singles 2025
• Round: Quarterfinals

All dates and times in this article are United States Eastern Time unless otherwise noted.

Dimers.com's comprehensive preview of Friday's Medvedev vs. Opelka match includes our prediction, picks and the latest betting odds.

Before making any Daniil Medvedev vs. Reilly Opelka picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Daniil Medvedev, with a 71% win probability, will likely beat Reilly Opelka at the ATP Libema Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Medvedev vs. Opelka insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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