Cubs vs. White Sox Prediction and Odds - May 29, 2022

The Chicago White Sox take on the Chicago Cubs in MLB action at Guaranteed Rate Field on Sunday, commencing at 2:10PM ET.

Dylan Cease (4-2, 4.24 ERA) will start on the mound for the White Sox, while the Cubs will counter with Marcus Stroman (2-4, 4.71 ERA).

Dimers' free betting picks for Cubs vs. White Sox, as well as game predictions and best odds, are detailed in this article.

This CHI Cubs vs. CHI White Sox betting preview is sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Cubs vs. White Sox?

Based on advanced machine learning and data, Dimers.com has simulated Sunday's Cubs-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the White Sox a 60% chance of defeating the Cubs.

More: Cubs vs. White Sox Simulated 10,000 Times

Cubs vs. White Sox Game Odds

• Run Line: White Sox -1.5 (+145), Cubs +1.5 (-160)
• Moneyline: White Sox -145, Cubs +130
• Total: Over/Under 7 (-120/+100)

Run Line, Moneyline and Over/Under

The White Sox are -1.5 favorites against the Cubs, with +145 at DraftKings Sportsbook the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -160.

Caesars Sportsbook currently has the best moneyline odds for the White Sox at -145. That means you can risk $145 to win $100, for a total payout of $245, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Cubs at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under for total runs scored sits at 7 with BetMGM, which currently has the best odds for the Over at -120, as well as the best odds for the Under at +100.

As always, check out all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 59% chance of covering the run line, while the Over/Under total of 7 runs is a 51% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Cubs vs. White Sox

• Run Line: White Sox -1.5 @ +145 via DraftKings Sportsbook (0.1% edge)
• Moneyline: White Sox @ -145 via Caesars Sportsbook (60% probability)
• Total: Under 7 @ +100 via BetMGM

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays 24/7/365.

Although the Cubs are more likely to cover the run line, our best bet of White Sox -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Furthermore, despite the Over being more likely to hit on this occasion, Under 7 is our best bet on account of the better odds (+100) that are available from BetMGM.

Cubs vs. White Sox Betting Guide

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full coverage of Sunday's Cubs-White Sox matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so refresh this article for any changes to our betting insights ahead of Cubs vs. White Sox on Sunday May 29, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cubs vs. White Sox 2022 Game Info

Sunday's matchup between the White Sox and Cubs at Guaranteed Rate Field is scheduled to start at 2:10PM ET.

• Who: Chicago White Sox vs. Chicago Cubs
• Date: Sunday May 29, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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What other MLB games are on today?

The Cubs and White Sox aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for each and every MLB game in our MLB Bet Hub section.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.