Cubs vs. Pirates Prediction and Odds - Apr 12, 2022

MLB action continues on Tuesday at 4:12PM EDT as the Chicago Cubs lock horns with the Pittsburgh Pirates at PNC Park.

The Pirates will send José Quintana (0-0, 0.00 ERA) to the mound, while the Cubs will counter with Drew Smyly (0-0, 0.00 ERA).

Dimers' top betting picks for Cubs vs. Pirates, as well as game predictions and best odds, are detailed below.

Who will win Cubs vs. Pirates?

Based on state-of-the-art computer power and data, Dimers.com has simulated Tuesday's Cubs-Pirates MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Cubs a 53% chance of defeating the Pirates.

More: Cubs vs. Pirates Simulated 10K Times

Cubs vs. Pirates Game Odds

• Run Line: Pirates +1.5, Cubs -1.5
• Moneyline: Pirates +100, Cubs -115
• Total: Over/Under 8.5

Run Line, Moneyline and Over/Under

The Pirates are +1.5 underdogs against the Cubs, with -160 at DraftKings Sportsbook the best odds currently available.

For the favored Cubs (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +146.

DraftKings Sportsbook currently has the best moneyline odds for the Pirates at +100, which means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Cubs at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under for total runs scored sits at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at -102.

As always, make sure you check all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 62% chance of covering the run line, while the 8.5-run Over/Under is a 51% chance of going Under.

More: Best Bets Today for All Major Sports

Best Bets for Cubs vs. Pirates

• Run Line: Pirates +1.5 @ -160 via DraftKings Sportsbook (62% probability)
• Moneyline: Cubs @ -115 via BetMGM (53% probability)
• Total: Under 8.5 @ -102 via FanDuel Sportsbook (51% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed investments with the legal sportsbooks in the United States.

Cubs vs. Pirates Probabilities

Use our widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. Pittsburgh, and click or tap on See Matchup for more.

Dimers has full coverage of Tuesday's Cubs-Pirates matchup, including pre-game predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so refresh this page for any changes to our betting insights before Cubs vs. Pirates on Tuesday April 12, 2022.

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Cubs vs. Pirates 2022 Game Info

When do the Pirates play the Cubs?

• Date: Tuesday April 12, 2022
• Time: 4:12PM EDT / 1:12PM PDT
• Venue: PNC Park

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It's only a click away, so why not take a look around?

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