Cubs vs. Padres Prediction and Odds - May 9, 2022

MLB action continues on Monday at 9:40PM ET as the Chicago Cubs lock horns with the San Diego Padres at PETCO Park.

MacKenzie Gore (2-0, 1.71 ERA) will start for the Padres, while the Cubs will counter with Kyle Hendricks (1-3, 5.64 ERA).

Dimers' top betting picks for Cubs vs. Padres, plus game predictions and best odds, are featured below.

This CHI Cubs vs. San Diego betting preview is sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Cubs vs. Padres?

Using trusted machine learning and data, Dimers.com has simulated Monday's Cubs-Padres MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Padres a 63% chance of winning against the Cubs.

More: Cubs vs. Padres Simulated 10,000 Times

Cubs vs. Padres Current Odds

• Run Line: Padres -1.5 (+130), Cubs +1.5 (-145)
• Moneyline: Padres -165, Cubs +155
• Total: Over/Under 7.5 (+100/-115)

Run Line, Moneyline and Over/Under

The Padres are currently -1.5 favorites against the Cubs, with +130 at PointsBet the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -145.

BetMGM currently has the best moneyline odds for the Padres at -165. That means you can risk $165 to win $100, for a total payout of $265, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Cubs at +155, where you can bet $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under for total runs scored is set at 7.5 with BetMGM, which currently has the best odds for the Over at +100, while Caesars Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 56% chance of covering the run line, while the 7.5-run Over/Under is a 52% chance of going Over.

More: Best Bets for Every MLB Game

Best Bets for Cubs vs. Padres

• Run Line: Padres -1.5 @ +130 via PointsBet (0.2% edge)
• Moneyline: Padres @ -165 via BetMGM (63% probability)
• Total: Over 7.5 @ +100 via BetMGM (52% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays every time.

Even though the Cubs are more likely to cover the run line, our best bet of Padres -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Cubs vs. Padres Betting Guide

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. San Diego, and click or tap on See Matchup for more.

Dimers has full betting coverage of Monday's Cubs-Padres matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this article for any changes to our betting analysis before Cubs vs. Padres on Monday May 9, 2022.

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Cubs vs. Padres 2022 Game Info

When do the Padres play the Cubs?

• Date: Monday May 9, 2022
• Time: 9:40PM ET / 6:40PM PT
• Venue: PETCO Park

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What other MLB games are on today?

The Cubs and Padres aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single MLB matchup via our MLB Predictions page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.