Cubs vs. D-Backs Prediction and Odds - May 14, 2022

The Arizona D-Backs and Chicago Cubs are scheduled to meet in MLB at Chase Field on Saturday, starting at 8:10PM ET.

Zac Gallen (2-0, 0.95 ERA) will be on the bump for the D-Backs, up against Kyle Hendricks (2-3, 4.38 ERA) for the Cubs.

Dimers' best betting picks for Cubs vs. D-Backs, plus game predictions and best odds, are detailed below.

This CHI Cubs vs. Arizona betting preview is presented by PointsBet, which has a 5x $100 Risk-Free Bets offer for new customers.

Who will win Cubs vs. D-Backs?

Using trusted computer power and data, Dimers.com has simulated Saturday's Cubs-D-Backs MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the D-Backs a 62% chance of defeating the Cubs.

More: Cubs vs. D-Backs Simulated 10K Times

Cubs vs. D-Backs Current Odds

• Run Line: D-Backs -1.5 (+135), Cubs +1.5 (-149)
• Moneyline: D-Backs -155, Cubs +140
• Total: Over/Under 8 (-110/-105)

Run Line, Moneyline and Over/Under

The D-Backs are -1.5 favorites against the Cubs, with +135 at DraftKings Sportsbook the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -149.

BetMGM currently has the best moneyline odds for the D-Backs at -155. That means you can risk $155 to win $100, for a total payout of $255, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Cubs at +140, where you can bet $100 to profit $140, earning a total payout of $240, if they win.

The Over/Under sits at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 57% chance of covering the run line, while the Over/Under total of 8 runs is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Cubs vs. D-Backs

• Run Line: D-Backs -1.5 @ +135 via DraftKings Sportsbook (0.5% edge)
• Moneyline: D-Backs @ -155 via BetMGM (62% probability)
• Total: Over 8 @ -110 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in America.

Although the Cubs are more likely to cover the run line, our best bet of D-Backs -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Cubs vs. D-Backs Betting Guide

Use our dynamic widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. Arizona, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Cubs-D-Backs matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Cubs vs. D-Backs on Saturday May 14, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cubs vs. D-Backs 2022 Game Info

Saturday's action between the D-Backs and Cubs at Chase Field will commence at 8:10PM ET.

• Date: Saturday May 14, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Chase Field

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Want more MLB analysis like this?

So, you liked our Cubs vs. D-Backs betting predictions? Awesome. Did you know our MLB Betting News page has a comprehensive betting preview for every MLB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets. This allows us to create the most authoritative MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.