Cubs vs. Cardinals Prediction and Odds - Jun 24, 2022

The St Louis Cardinals take on the Chicago Cubs in MLB action at Busch Stadium on Friday, beginning at 8:15PM ET.

The Cardinals will send Andre Pallante (2-2, 1.69 ERA) to the mound, while the Cubs will counter with Kyle Hendricks (2-6, 5.43 ERA).

Dimers' top betting picks for Cubs vs. Cardinals, as well as game predictions and best odds, are featured below.

Who will win Cubs vs. Cardinals?

Using advanced computer power and data, Dimers.com has simulated Friday's Cubs-Cardinals MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Cardinals a 64% chance of defeating the Cubs.

More: Cubs vs. Cardinals Simulated 10K Times

Cubs vs. Cardinals Game Odds

• Run Line: Cardinals -1.5 (+115), Cubs +1.5 (-130)
• Moneyline: Cardinals -165, Cubs +155
• Total: Over/Under 9 (-105/-115)

Run Line, Moneyline and Over/Under

The Cardinals are listed as -1.5 favorites against the Cubs, with +115 at BetMGM the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -130.

BetMGM currently has the best moneyline odds for the Cardinals at -165, which means you can risk $165 to win $100, for a total payout of $265, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Cubs at +155, where you can put down $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under for total runs scored is set at 9 with Caesars Sportsbook, which currently has the best odds for the Over at -105, as well as the best odds for the Under at -115.

As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 9 runs is a 53% chance of going Under.

More: Live Scores for All Major Sports

Best Bets for Cubs vs. Cardinals

• Run Line: Cardinals -1.5 @ +115 via BetMGM
• Moneyline: Cardinals @ -165 via BetMGM (64% probability)
• Total: Under 9 @ -115 via Caesars Sportsbook (53% probability)

Dimers' best bets are based on detailed simulations and gambling expertise to bring you the best possible plays 24/7.

Even though the Cubs are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Cubs vs. Cardinals Prediction

Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI Cubs vs. St Louis, and click or tap on See Matchup for more.

Dimers has full coverage of Friday's Cubs-Cardinals matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this page for the latest betting insights ahead of Cubs vs. Cardinals on Friday June 24, 2022.

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Cubs vs. Cardinals 2022 Game Info

Friday's matchup between the Cardinals and Cubs at Busch Stadium is scheduled to start at 8:15PM ET.

• Who: St Louis Cardinals vs. Chicago Cubs
• Date: Friday June 24, 2022
• Time: 8:15PM ET / 5:15PM PT
• Venue: Busch Stadium

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