Creighton vs. Southern Illinois CBB Predictions and Odds - Nov 22, 2021

Southern Illinois faces the favored Creighton in College Basketball action at Virgin Islands Sport & Fitness Center on Monday, beginning at 5:45 PM EST.

Dimers' best betting picks for Creighton vs. Southern Illinois, plus game predictions and best odds, are detailed in this article.

Who will win Creighton vs. Southern Illinois?

Based on advanced machine learning and data, Dimers.com has simulated Monday's Creighton-Southern Illinois NCAA Basketball game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Creighton a 68% chance of winning against Southern Illinois.

MORE: Creighton vs. Southern Illinois Simulated 10,000 Times

Creighton vs. Southern Illinois Point Spread, Moneyline and Over/Under

Southern Illinois is listed as the +5.5 underdog against Creighton, with -102 at FanDuel Sportsbook the best odds available.

For the favored Creighton (-5.5) to cover the spread, BetMGM has the best odds on offer at -110.

FanDuel Sportsbook has the best moneyline odds for Southern Illinois at +230. That means you can throw down $100 to profit $230, earning a total payout of $330, if it wins.

Meanwhile, PointsBet has the best moneyline odds for Creighton at -240, where you can risk $240 to win $100, for a total payout of $340, if it comes out on top.

The Over/Under sits at 135.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, Southern Illinois (+5.5) is a 57% chance of covering the spread, while the 135.5-point Over/Under is a 54% chance of going Under.

MORE: Live Win Probabilities for All Major College Sports

Best Bets for Creighton vs. Southern Illinois

• Spread: Southern Illinois +5.5 at -102 with FanDuel Sportsbook (57% probability) 🔥
• Moneyline: Southern Illinois Win at +230 with FanDuel Sportsbook (2.6% edge)
• Over/Under: Under 135.5 at -110 with BetMGM (54% probability)

Every time you see a 🔥, that means you've found one of our best free picks today across any sport.

While Creighton is more likely to win the game, according to DimersBOT, betting on Southern Illinois moneyline is the best option because of the 2.6% edge identified when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges seen on Dimers.com is pivotal to being a profitable sports bettor in the long run.

Creighton vs. Southern Illinois Score Prediction

Dimers.com's predicted final score for Creighton vs. Southern Illinois at Virgin Islands Sport & Fitness Center on Monday has Creighton winning 69-64.

Use our interactive widget below to see the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full betting coverage of Monday's Creighton-Southern Illinois matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this article for the latest betting insights ahead of Creighton vs. Southern Illinois on Monday November 22, 2021.

Creighton vs. Southern Illinois 2021 CBB Game Info

When does Southern Illinois play Creighton in College Basketball?

• Date: Monday November 22, 2021
• Time: 5:45 PM EST / 2:45 PM PST
• Venue: Virgin Islands Sport & Fitness Center

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The Sleepers Podcast 🏀 Best Bets

The Sleepers Podcast, part of the Dimers Podcast Network, covers all things College Hoops, including the picks below to help you find the winning edge.

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