Cowboys vs. 49ers Prediction and Odds - Jan 22, 2023

NFL action continues on Sunday at 6:30PM ET as the Dallas Cowboys square off with the San Francisco 49ers in the Divisional Round of the NFL Playoffs at Levi's Stadium.

Dimers' best betting picks for Cowboys vs. 49ers, as well as game predictions, betting odds and projected player stats, are featured below.

Who will win Cowboys vs. 49ers?

Based on cutting-edge machine learning and data, Dimers.com has simulated Sunday's Cowboys-49ers NFL matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the 49ers a 65% chance of defeating the Cowboys.

More: Cowboys vs. 49ers Simulated 10,000 Times

Cowboys vs. 49ers Odds

• Spread: 49ers -3.5 (-105), Cowboys +3.5 (-110)
• Moneyline: 49ers -174, Cowboys +165
• Total: Over/Under 46.5 (-110/-110)

Point Spread, Moneyline and Over/Under

The 49ers are listed as -3.5 favorites against the Cowboys, with -105 at FanDuel Sportsbook the best odds currently available.

For the underdog Cowboys (+3.5) to cover the spread, PointsBet has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for the 49ers at -174. That means you can risk $174 to win $100, for a total payout of $274, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Cowboys at +165, where you can bet $100 to profit $165, earning a total payout of $265, if they win.

The Over/Under for total points scored is set at 46.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the 49ers (-3.5) are a 52% chance of covering the spread, while the Over/Under total of 46.5 points is considered an equal 50-50 chance of hitting.

More: Best Bets Today for All Major Sports

Best Bets for Cowboys vs. 49ers

• Spread: 49ers -3.5 @ -105 via FanDuel Sportsbook (52% probability)
• Moneyline: 49ers @ -174 via FanDuel Sportsbook (65% probability)
• Total: Under 46.5 @ -110 via PointsBet (50% probability)

Our best bets are based on detailed simulations and wagering intelligence to help you make better investments with the legal sportsbooks in your state.

Cowboys vs. 49ers Prediction

Dimers.com's predicted final score for Dallas vs. San Francisco at Levi's Stadium on Sunday has the 49ers winning 25-21.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Cowboys-49ers matchup, including pregame predictions, best betting picks, and live win probabilities.

Cowboys vs. 49ers Player Props

Who will score an anytime touchdown in Cowboys vs. 49ers? The latest data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Cowboys and 49ers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you choose the best prop bets for Sunday's game.

According to DimersBOT, San Francisco's Christian McCaffrey is most likely to score the first touchdown in Cowboys vs. 49ers.

DimersBOT gives McCaffrey an 11.8% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 49.7% chance of scoring an anytime touchdown.

Scroll down for the full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Dallas Cowboys

• Ezekiel Elliott: 11.4% probability
• CeeDee Lamb: 9.2% probability
• Tony Pollard: 7.7% probability
• Dalton Schultz: 5.4% probability
• Dak Prescott: 4.5% probability

San Francisco 49ers

• Christian McCaffrey: 11.8% probability
• George Kittle: 10.3% probability
• Deebo Samuel: 8.6% probability
• Brandon Aiyuk: 6.6% probability
• Elijah Mitchell: 4.2% probability

Anytime Touchdown Scorer Probabilities

Dallas Cowboys

• Ezekiel Elliott: 46.7% probability
• CeeDee Lamb: 40.2% probability
• Tony Pollard: 34.2% probability
• Dalton Schultz: 25.6% probability
• Dak Prescott: 22.6% probability

San Francisco 49ers

• Christian McCaffrey: 49.7% probability
• George Kittle: 44.1% probability
• Deebo Samuel: 38.7% probability
• Brandon Aiyuk: 31.5% probability
• Elijah Mitchell: 21.4% probability

Cowboys-49ers Projected Player Stats

Of the starting quarterbacks, the Cowboys' Dak Prescott is projected for 223 passing yards, while the 49ers' Brock Purdy is expected to throw for 230 yards.

Cowboys Starting QB

• Dak Prescott: 223 projected yards

49ers Starting QB

• Brock Purdy: 230 projected yards

Cowboys Rushing

• Tony Pollard: 58 projected yards
• Ezekiel Elliott: 49 projected yards
• Dak Prescott: 15 projected yards

49ers Rushing

• Christian McCaffrey: 70 projected yards
• Elijah Mitchell: 35 projected yards
• Deebo Samuel: 21 projected yards

Cowboys Receiving

• CeeDee Lamb: 80 projected yards
• Dalton Schultz: 44 projected yards
• Michael Gallup: 36 projected yards
• T.Y. Hilton: 29 projected yards
• Tony Pollard: 20 projected yards

49ers Receiving

• Deebo Samuel: 67 projected yards
• Brandon Aiyuk: 56 projected yards
• George Kittle: 47 projected yards
• Christian McCaffrey: 41 projected yards
• Jauan Jennings: 22 projected yards

Don't forget, DimersBOT updates often, so refresh this page for the latest betting insights ahead of Cowboys vs. 49ers on Sunday January 22, 2023.

Cowboys vs. 49ers 2023

Sunday's game between the 49ers and Cowboys at Levi's Stadium is scheduled to commence at 6:30PM ET.

• Who: Dallas Cowboys vs. San Francisco 49ers
• Date: Sunday January 22, 2023
• Time: 6:30PM ET / 3:30PM PT
• Venue: Levi's Stadium

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