UConn vs. Xavier prediction: Connecticut favored to win men's college basketball matchup [12/31/2025]

Xavier will face the favored UConn in men's college basketball action at Cintas Center on Wednesday, commencing at 5:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model projects Connecticut as the most likely winner of the UConn vs. Xavier game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

UConn vs. Xavier prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between UConn and Xavier 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Connecticut an 82% chance of defeating Xavier. Our predicted final score has Connecticut winning 77-67.

According to our model, Xavier (+11.5) has a 56% chance of covering the spread, while the 143.5-point over/under has a 53% chance of going over.

UConn vs. Xavier odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

UConn vs. Xavier picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: