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Colgate vs. Lafayette prediction: Colgate favored to win men's college basketball matchup [12/31/2025]

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Written by Mac Douglass

Get Colgate vs Lafayette predictions for college basketball Wednesday.

Colgate-Lafayette Predictions and Game Preview.
Colgate vs. Lafayette men's college basketball prediction for Wednesday, December 31, 2025.

Lafayette will take on the favored Colgate in men's college basketball action at Kirby Sports Center on Wednesday, beginning at 3:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Colgate as the most likely winner of the Colgate vs. Lafayette game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Colgate vs. Lafayette prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Colgate and Lafayette 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Colgate a 75% chance of beating Lafayette. Our predicted final score has Colgate winning 76-69.

According to our model, Colgate (-6.5) has a 55% chance of covering the spread, while the 146.5-point over/under has a 52% chance of staying under.

 

Colgate vs. Lafayette odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Colgate Lafayette
Spread -6.5 (-105) +6.5 (-108)
Moneyline -285 +240
Total o146.5 (-110) u146.5 (-106)

All odds are correct at the time of publication and are subject to change.

Colgate vs. Lafayette picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Colgate -6.5 -105
Moneyline Colgate -285
Total Under 146.5 -106

According to our men's college basketball best bets, the top play to make on this game is Colgate -6.5 at the spread.

 

Colgate vs. Lafayette game-day updates and essential details

Wednesday's men's college basketball action between Lafayette and Colgate at Kirby Sports Center is scheduled to begin at 3:00 PM ET.

  • Who: Colgate vs. Lafayette
  • Date: Wednesday, December 31, 2025
  • Time: 3:00 PM ET/12:00PM PT
  • Venue: Kirby Sports Center

Conclusion

We predict Colgate, with a 75% win probability, will likely beat Lafayette on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Colgate vs. Lafayette insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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