Colgate vs. Lafayette prediction: Colgate favored to win men's college basketball matchup [12/31/2025]

Men's college basketball action continues on Wednesday at 3:00 PM ET as the favored Colgate squares off with Lafayette in men's college basketball action at Kirby Sports Center.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Colgate as the most likely winner of the Colgate vs. Lafayette game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Colgate vs. Lafayette prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball matchup between Colgate and Lafayette 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Colgate a 77% chance of defeating Lafayette. Our predicted final score has Colgate winning 76-69.

According to our model, the bookmakers have got it right, and Colgate and Lafayette each have a 50% chance of covering the spread, while the over/under total of 146.5 points also has an equal 50-50 chance of hitting.

Colgate vs. Lafayette odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Colgate vs. Lafayette picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: