Clemson vs. Virginia CBB Predictions and Odds - Dec 22, 2021

Virginia takes on Clemson in College Basketball action at John Paul Jones Arena on Wednesday, commencing at 7:00PM EST.

Dimers' free betting picks for Clemson vs. Virginia, as well as our score prediction and best odds, are detailed below.

Who will win Clemson vs. Virginia?

Using advanced machine learning and data, Dimers.com has simulated Wednesday's Clemson-Virginia NCAA Basketball matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives Virginia a 63% chance of beating Clemson.

MORE: Clemson vs. Virginia Simulated 10K Times

Point Spread, Moneyline and Over/Under

Virginia is currently the -3.5 favorite versus Clemson, with -110 at BetMGM the best odds available.

For the underdog Clemson (+3.5) to cover the spread, BetMGM also has the best odds on offer at -110.

PointsBet has the best moneyline odds for Virginia at -185, which means you can risk $185 to win $100, for a total payout of $285, if it gets the W.

Elsewhere, DraftKings Sportsbook has the best moneyline odds for Clemson at +170, where you can bet $100 to profit $170, earning a total payout of $270, if it wins.

The Over/Under is set at 120 with DraftKings Sportsbook, which has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all the sportsbooks available in your state for the best College Basketball odds and lines.

According to DimersBOT, Clemson (+3.5) is a 61% chance of covering the spread, while the 120-point Over/Under is a 59% chance of going Over.

MORE: Live Scores for All Major College Sports

Best Bets for Clemson vs. Virginia

• Spread: Clemson +3.5 at -110 with BetMGM (61% probability) 🔥
• Moneyline: Virginia Win at -185 with PointsBet (63% probability)
• Over/Under: Over 120 at +100 with DraftKings Sportsbook (59% probability) 🔥

Any time you see a 🔥, you know you've found one of Dimers' best free picks of the day across any sport.

Clemson vs. Virginia Score Prediction

Dimers.com's predicted final score for Clemson vs. Virginia at John Paul Jones Arena this Wednesday has Virginia winning 57-54.

Use our widget below to view the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Clemson-Virginia matchup, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this article for the latest betting insights before Clemson vs. Virginia on Wednesday December 22, 2021.

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Clemson vs. Virginia 2021 CBB Game Info

When does Virginia play Clemson in College Basketball?

• Date: Wednesday December 22, 2021
• Time: 7:00PM EST / 4:00PM PST
• Venue: John Paul Jones Arena

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What College Basketball games are on tonight?

Clemson and Virginia aren't the only two NCAA Basketball teams you can bet on. DimersBOT never stops and we've got picks and top bets for each and every CBB game in our College Basketball Bet Hub page.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out today!