Clemson vs. Louisville CBB Predictions and Odds - Feb 19, 2022

Louisville and Clemson are scheduled to meet in College Basketball action at KFC Yum! Center on Saturday, starting at 3:00PM EST.

Dimers' free betting picks for Clemson vs. Louisville, plus game predictions and best odds, are featured in this article.

Who will win Clemson vs. Louisville?

Using trusted computer power and data, Dimers.com has simulated Saturday's Clemson-Louisville NCAA Basketball game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, can't split the two teams, giving both Clemson and Louisville a 50% chance of winning the game.

MORE: Full Betting Analysis for Clemson vs. Louisville

Point Spread, Moneyline and Over/Under

Louisville is the +1.5 underdog against Clemson, with -115 at DraftKings Sportsbook the best odds currently available.

For the favored Clemson (-1.5) to cover the spread, BetMGM has the best odds currently on the market at +100.

FanDuel Sportsbook currently has the best moneyline odds for Louisville at +102. That means you can bet $100 to profit $102, earning a total payout of $202, if it wins.

Elsewhere, PointsBet currently has the best moneyline odds for Clemson at -115, where you can risk $115 to win $100, for a total payout of $215, if it comes out on top.

The Over/Under is set at 136.5 with PointsBet, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best College Basketball odds and lines.

According to DimersBOT, Louisville (+1.5) is a 58% chance of covering the spread, while the 136.5-point Over/Under is a 52% chance of going Under.

MORE: Best Bets Today for All Major College Sports

Best Bets for Clemson vs. Louisville

• Spread: Louisville +1.5 at -115 with DraftKings Sportsbook (58% probability) 🔥
• Moneyline: Louisville at +102 with FanDuel Sportsbook (50% probability)
• Over/Under: Under 136.5 at -110 with BetMGM (52% probability)

When you see a 🔥, you know you've found one of our best bets of the day across all sports.

Dimers' best bets are based on detailed simulations and betting intelligence to help you make more informed investments.

Clemson vs. Louisville Score Prediction

Dimers.com's predicted score for Clemson vs. Louisville at KFC Yum! Center this Saturday is Clemson 68-68 Louisville.

While there is no way for a College Basketball game to end in a tie, our prediction of 68-68 is based on each team's average score after 10,000 simulations by DimersBOT.

Use our interactive widget below to explore the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Clemson-Louisville matchup, including pre-game predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so check this article for any changes to our betting insights before Clemson vs. Louisville on Saturday February 19, 2022.

Best Betting Offer for Clemson vs. Louisville

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Clemson vs. Louisville. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Clemson vs. Louisville 2022 CBB Game Info

When does Louisville play Clemson in College Basketball?

• Date: Saturday February 19, 2022
• Time: 3:00PM EST / 12:00PM PST
• Venue: KFC Yum! Center

Ready to join an online sportsbook and start betting on College Basketball now? We've got access to the best available sign-up offers in each legal betting state.

Want more CBB analysis like this?

To get more NCAA Basketball betting predictions like you've just read for Clemson vs. Louisville, all you've gotta do is visit Dimers' College Basketball Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the best CBB betting previews out there. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.