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Clemson vs. BYU prediction: BYU favored to win men's college basketball matchup [12/9/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Clemson vs BYU predictions for college basketball Tuesday.
BYU and Clemson will lock horns in men's college basketball action at Madison Square Garden on Tuesday, with tipoff at 6:30PM ET.
Based on updated simulation results, Dimers' advanced college basketball model predicts BYU as the most likely winner of the Clemson vs. BYU game.
This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Clemson vs. BYU prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball game between Clemson and BYU 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives BYU a 67% chance of defeating Clemson. Our predicted final score has BYU winning 78-73.
According to our model, the bookmakers have got it right, and Clemson and BYU each have a 50% chance of covering the spread, while the 152.5-point over/under has a 52% chance of staying under.
Clemson vs. BYU odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Clemson | BYU |
|---|---|---|
| Spread | +4.5 (-102) | -4.5 (-110) |
| Moneyline | +190 | -210 |
| Total | o152.5 (-110) | u152.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Clemson vs. BYU picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Clemson +4.5 | -102 |
| Moneyline | Clemson | +190 |
| Total | Under 152.5 | -110 |
According to our best men's college basketball bets, the top play to make on this game is Clemson +4.5 at the spread.
Clemson vs. BYU game-day updates and essential details
Tuesday's men's college basketball game between BYU and Clemson at Madison Square Garden is scheduled to begin at 6:30PM ET.
- Who: Clemson vs. BYU
- Date: Tuesday, December 9, 2025
- Time: 6:30PM ET/3:30PM PT
- Venue: Madison Square Garden
Conclusion
We predict BYU, with a 67% win probability, will likely beat Clemson on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Clemson vs. BYU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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